What's Love Got to do with it: Role of oxytocin in trauma, attachment and resilience

SR Sharma, X Gonda, P Dome, FI Tarazi - Pharmacology & Therapeutics, 2020 - Elsevier
Oxytocin (OT) is a neurohypophysial hormone and neuropeptide produced by the
hypothalamus and released by the pituitary gland. It has multiple physiological roles …

Is oxytocin “nature's medicine”?

CS Carter, WM Kenkel, EL MacLean, SR Wilson… - Pharmacological …, 2020 - ASPET
Oxytocin is a pleiotropic, peptide hormone with broad implications for general health,
adaptation, development, reproduction, and social behavior. Endogenous oxytocin and …

Roles of oxytocin in stress responses, allostasis and resilience

Y Takayanagi, T Onaka - International journal of molecular sciences, 2021 - mdpi.com
Oxytocin has been revealed to work for anxiety suppression and anti-stress as well as for
psychosocial behavior and reproductive functions. Oxytocin neurons are activated by …

Oxytocin: the great facilitator of life

HJ Lee, AH Macbeth, JH Pagani, WS Young 3rd - Progress in neurobiology, 2009 - Elsevier
Oxytocin (Oxt) is a nonapeptide hormone best known for its role in lactation and parturition.
Since 1906 when its uterine-contracting properties were described until 50 years later when …

Oxytocin and interpersonal relationships

A Patin, D Scheele, R Hurlemann - Behavioral Pharmacology of …, 2018 - Springer
The neuropeptide oxytocin (OT) has emerged as a potent modulator of diverse aspects of
interpersonal relationships. OT appears to work in close interaction with several other …

Oxytocin and stress-related disorders: neurobiological mechanisms and treatment opportunities

LM Sippel, CE Allington, RH Pietrzak… - Chronic …, 2017 - journals.sagepub.com
Novel pharmacotherapies that improve outcomes for individuals with stress-related
psychiatric disorders are needed. The neurohormone oxytocin (OT) is a promising candidate …

[HTML][HTML] The associations between oxytocin and trauma in humans: a systematic review

MF Donadon, R Martin-Santos, FL Osorio - Frontiers in pharmacology, 2018 - frontiersin.org
Studies have shown that traumatic experiences may affect hormonal systems mediated by
the hypothalamic-pituitary-adrenal (HPA) axis and the oxytocinergic system. This effect is the …

[HTML][HTML] Oxytocin and social motivation

I Gordon, C Martin, R Feldman, JF Leckman - Developmental cognitive …, 2011 - Elsevier
Humans are fundamentally social creatures who are 'motivated'to be with others. In this
review we examine the role of oxytocin (OT) as it relates to social motivation. OT is …

Oxytocin role in enhancing well-being: a literature review

WW IsHak, M Kahloon, H Fakhry - Journal of affective disorders, 2011 - Elsevier
OBJECTIVES: Oxytocin (OT) has long been implicated in maternal bonding, sexual behavior
and social affiliation behaviors. This paper reviews the wide effects of oxytocin and its key …

[HTML][HTML] Dissecting the role of oxytocin in the formation and loss of social relationships

R Hurlemann, D Scheele - Biological Psychiatry, 2016 - Elsevier
Current concepts of human sociality highlight a fundamental role of the hypothalamic
peptide oxytocin (OXT) in the formation and maintenance of social relationships. However …