Neuroprotective effects of cryptotanshinone in a direct reprogramming model of Parkinson's disease

JE Lee, H Sim, HM Yoo, M Lee, A Baek, YJ Jeon… - Molecules, 2020 - mdpi.com
Parkinson's disease (PD) is a well-known age-related neurodegenerative disease.
Considering the vital importance of disease modeling based on reprogramming technology …

Cryptotanshinone protects against oxidative stress in the paraquat‐induced Parkinson's disease model

JM Sun, S Agarwal, TD Desai, DT Ju… - Environmental …, 2023 - Wiley Online Library
Parkinson's disease (PD) is a common neurodegenerative disorder associated with striatal
dopaminergic neuronal loss in the Substantia nigra. Oxidative stress plays a significant role …

Neuroprotective effects of cryptotanshinone and 1, 2-dihydrotanshinone I against MPTP induced mouse model of Parkinson's disease

G Cao, X Wang, K Li, A Zhao, L Shen, D Yu - Phytochemistry letters, 2018 - Elsevier
dihydrotanshinone I (DTs1) and cryptotanshinone (CTs) are the two major compounds
isolated from Salvia castanea f. tomentosa Stib., which possess diverse biological effects …

Cryptotanshinone ameliorates MPP+-induced oxidative stress and apoptosis of SH-SY5Y neuroblastoma cells: the role of STAT3 in Parkinson's disease

Q Wang, Y Liu - Metabolic Brain Disease, 2022 - Springer
Cryptotanshinone (CTN) has shown its neuroprotective and anti-inflammatory qualities in
non-genetic mouse model of Alzheimer's disease. According to bioinformatics analysis, CTN …

Protective effect of chinonin in MPTP-induced C57BL/6 mouse model of Parkinson's disease

G Feng, Z Zhang, Q Bao, Z Zhang, L Zhou… - Biological and …, 2014 - jstage.jst.go.jp
The aims of this study were to investigate the effect of chinonin in preventing 1-methyl-4-
phenyl-1, 2, 3, 6-tetrahydropyridine (MPTP)-induced neurodegeneration in C57BL/6 mice …

Recent advances on the neuroprotective potential of antioxidants in experimental models of Parkinson's disease

S Koppula, H Kumar, SV More, BW Kim, IS Kim… - International journal of …, 2012 - mdpi.com
Parkinson's disease (PD), a neurodegenerative movement disorder of the central nervous
system (CNS) is characterized by a progressive loss of dopaminergic neurons in the …

[HTML][HTML] Enhanced neuroprotective effects of coadministration of tetrandrine with glutathione in preclinical model of Parkinson's disease

XY Li, GH Mei, Q Dong, Y Zhang, ZL Guo, JJ Su… - Parkinson's …, 2015 - hindawi.com
Aim. In this study we examined the influence of tetrandrine (Tet) on the neuroprotective
effects of glutathione (GSH) in the 6-hydroxydopamine-(6-OHDA-) lesioned rat model of …

β-Caryophyllene exerts protective antioxidant effects through the activation of NQO1 in the MPTP model of Parkinson's disease

ME Flores-Soto, JA Corona-Angeles… - Neuroscience …, 2021 - Elsevier
Parkinson's disease (PD) is a neurodegenerative disorder, caused by the selective death of
dopaminergic neurons in the substantia nigra pars compacta. β-caryophyllene (BCP) is a …

[HTML][HTML] Neuroprotection of indole-derivative compound NC001-8 by the regulation of the NRF2 pathway in Parkinson's disease cell models

PC Wei, GJ Lee-Chen, CM Chen, YR Wu… - … medicine and cellular …, 2019 - hindawi.com
Parkinson's disease (PD) is a common neurodegenerative disease accompanied by a loss
of dopaminergic (DAergic) neurons. The development of therapies to prevent disease …

Cellular and molecular mechanisms underly the combined treatment of fasudil and bone marrow derived-neuronal stem cells in a Parkinson's disease mouse model

YC Yan, Y Li, BG Xiao, J Wang, JY Xi, WB Yu - Molecular Neurobiology, 2023 - Springer
Bone marrow-derived neural stem cells (BM-NSCs) have shed light on novel therapeutic
approaches for PD with the potential to halt or even reverse disease progression. Various …