Berberine as an Efflux Pump Inhibitor against Quinolone Resistant Staphylococcus aureus

M Arya, AR Nisha, S Sujith, SS Rani, N Thomas - 2023 - indianjournals.com
The emergence of antibiotic resistance has led to the search for novel strategies that can
overcome this issue. In this connection, the plant secondary metabolites play a crucial role in …

[HTML][HTML] Enhanced Efficacy of Ciprofloxacin and Tobramycin against Staphylococcus aureus When Combined with Corydalis Tuber and Berberine through Efflux …

Y Seo, M Kim, TJ Kim - Antibiotics, 2024 - mdpi.com
One way that bacteria develop antibiotic resistance is by reducing intracellular antibiotic
concentrations through efflux pumps. Therefore, enhancing the efficacy of antibiotics using …

Hormesis Effect of Berberine against Klebsiella pneumoniae Is Mediated by Up-Regulation of the Efflux Pump KmrA

Y Li, H Wen, X Ge - Journal of Natural Products, 2021 - ACS Publications
Berberine (BBR) is an effective drug for human intestinal inflammation by preventing
intestinal adhesion of bacterial pathogens, while its antibacterial activity is ineffective …

[PDF][PDF] Synergism between natural products and fluoroquinolones against Staphylococcus aureus strains

U Sharma, S Jandaik, J Mehta, MM Sharma - researchgate.net
The impact of Staphylococcus aureus infections on human health has led to intensive
investigation of this organism over recent years. Antibiotic resistance in Staphylococcus …

In Vitro and In Silico Inhibition of Staphylococcus aureus Efflux Pump NorA by α-Pinene and Limonene

ACJ de Araújo, PR Freitas, CR dos Santos Barbosa… - Current …, 2021 - Springer
Since the discovery of the first antibiotics, bacteria have acquired a variety of resistance
mechanisms, with efflux pump (EP) being the most prominent mechanism for intracellular …

[PDF][PDF] Efflux inhibitory activity of flavonoids from Chromolaena odorata against selected methicillin-resistant Staphylococcus aureus (MRSA) isolates

SA Johari, LS Kiong, M Mohtar, MM Isa, S Man… - Afr J Microbiol …, 2012 - researchgate.net
Staphylococcus aureus (MRSA) isolates with active efflux properties. Only low inhibitory
potential were detected through the preliminary evaluation as indicated by their respective …

Evaluation of efflux pump inhibitory activity of some plant extracts and using them as adjuvants to potentiate the inhibitory activity of some antibiotics against …

D Al-Sallami, A Alsultan, KH Abbas, SR Clarke - Open Veterinary Journal, 2023 - ajol.info
Background: Antibiotic-resistant pathogens became a real global threat to human and
animal health. This needs to concentrate the efforts to minimize and control these …

[HTML][HTML] Inhibitory effects of silybin on the efflux pump of methicillin‑resistant Staphylococcus aureus

D Wang, K Xie, D Zou, M Meng… - Molecular medicine …, 2018 - spandidos-publications.com
Bacterial multidrug resistance efflux systems serve an important role in antimicrobial
resistance. Thus, identifying novel and effective efflux pump inhibitors that are safe with no …

[PDF][PDF] Mangifera indica crude leaf extracts inhibits efflux pump system in Serratia marscencens

BT Thomas, AA Olanpeleke, OM Lakunle… - Global Journal of …, 2015 - academia.edu
This study evaluated the phytochemical constituents and the anti efflux pump activity of
Mangifera indica Linn leaves against the strains of efflux positive Serratia marscencens …

[HTML][HTML] Essential oil, extracts, and sesquiterpenes obtained from the heartwood of pilgerodendron uviferum act as potential inhibitors of the Staphylococcus aureus …

J Espinoza, A Urzúa, L Sanhueza, M Walter… - Frontiers in …, 2019 - frontiersin.org
Staphylococcus aureus is a serious human pathogen that is highly adaptive to
environmental conditions and rapidly develops antibiotic resistance. The use of efflux pumps …