The value of serum tumor biomarkers used for lung cancer diagnosis is still controversial in
clinical practice. This study aimed to further dissect and evaluate the clinical value of serum …

Background Human epididymis protein 4 (HE4) had been shown to be an ideal biomarker in
ovarian cancer. However, there were fewer reports on its application in lung cancer. We …

Objective This study aimed to explore the application value of human epididymis protein 4
(HE4) in diagnosing and monitoring the prognosis of lung cancer. Methods First, TCGA (The …

Background: Human epididymis protein 4 (HE4) is a reliable tumor marker for ovarian
cancer, but only limited data are available on HE4 levels in lung malignancies. Methods …

Lung cancer (LC) is the most frequently diagnosed cancer and is the leading cause of
cancer‑associated death. Serum markers that exhibit high sensitivity and specificity for LC …

Background: The aim of our study was to assess the value of serum human epididymis
protein 4 (HE4) to diagnose lung cancer and provide reliable scientific conclusions to guide …

Background and aim Early diagnosis and histological subtyping are important issues in the
management of patients with lung cancer (LC). The aim of this study is to investigate the …

Abstract Human epididymis protein 4 (HE4) has been suggested as a useful new biomarker
of lung cancer; however, few relevant large-scale studies have been published. In this study …

Objectives This study aimed to assess the diagnostic value of human epididymal protein 4
(HE4), a potential novel biomarker for lung cancer, and its combined detection with five other …

We evaluated the expression and diagnostic value of human epididymis protein 4 (HE4) in
small cell lung cancer (SCLC). Serum HE4 level was measured in serum samples from 30 …