OBJECTIVE: This study aimed to assess the diagnostic value of human epididymis protein 4
(HE4) in the pleural effusion of lung cancer patients. METHODS: HE4 protein in the pleural …

Background Lung cancer (LC) is one of the most common types of malignant tumors and is
the most prominent cause of tumor-related death worldwide. LC is a heterogeneous disease …

Background With the increasing prevalence of lung cancer, it has become imperative to
identify reliable biomarkers that can aid in early detection and prognosis assessment …

Abstract Human epididymis protein 4 (HE4) acts as a protease inhibitor. It has been detected
in the serum of patients with lung cancer patients and its utility for lung cancer screening was …

The diagnostic value of serum HE4 in patients with lung cancer remains controversial. Thus,
we performed a systematic review and meta‐analysis to assess the diagnostic accuracy of …

Objective The aim of this study was to assess the clinical value of pro-gastrin releasing
peptide (ProGRP), squamous cell carcinoma antigen (SCC-Ag), cytokeratin 19 fragment …

Lung cancer is the leading cause of cancer related deaths. Despite the modern diagnostic
and therapeutic advances, 5-year survival rate of all cases of lung cancer does not exceed …

The prognostic significance of serum human epididymis protein 4 (HE4) levels in human
NSCLC among a Chinese population has not been investigated. The purpose of this study …

Human epididymis secretory protein 4 (HE4) is a secreted glycosylated protein encoded by
the WAP four-disulfide core domain 2 (WFDC2) gene, located on a chromosome 20 …

An effective blood test is valuable to aid clinicians in making case management decisions.
The present study was to analyze the value of four serum tumor markers for the diagnosis of …