The cellular and molecular mechanisms of tumor angiogenesis and its prospects for anti-
angiogenic cancer therapy are major issues in almost all current concepts of both cancer …

Angiogenesis is a central feature of glioblastoma (GBM), with contribution from several
mechanisms and signaling pathways to produce an irregular, poorly constructed, and poorly …

Structural and functional abnormalities of the vascular microenvironment determine
pathophysiological characteristics of gliomas, such as loss of blood–brain barrier function …

Glioblastomas are highly vascular tumors. Recent preclinical and clinical investigations
have revealed that agents targeting angiogenesis may have efficacy against this type of …

Structural and functional abnormalities of the vascular microenvironment determine
pathophysiological characteristics of gliomas, such as loss of blood-brain barrier function …

Simple Summary Glioblastoma is the most common malignant primary brain tumor. Despite
technological advancements and modern therapeutic agents used for treatment, the …

Despite advances in surgery, radiation therapy, and chemotherapeutics, patients with
malignant glioma have a dismal prognosis. The formations of aberrant tumour vasculature …

Glioblastoma is the most aggressive brain tumor with a median survival of less than 15
months. The complex interactions between the tumor and the cells of the tumor …

Glioblastomas (GBMs), the most common primary brain tumor in adults, are characterized by
resistance to chemotherapy and radiotherapy. One of the defining characteristics of GBM is …

Glioblastoma multiforme (GBM) is the most malignant brain tumor and highly resistant to
intensive combination therapies. GBM is one of the most vascularized tumors and vascular …