In Vitro Synergistic Activity of Antimicrobial Combinations against Carbapenem- and Colistin-Resistant Acinetobacter baumannii and Klebsiella pneumoniae

P Mantzana, E Protonotariou, A Kassomenaki… - Antibiotics, 2023 - mdpi.com
Polymyxins are commonly used as the last resort for the treatment of MDR Acinetobacter
baumannii and Klebsiella pneumoniae nosocomial infections; however, apart from the …

In-Vitro Evaluation of Different Antimicrobial Combinations with and without Colistin Against Carbapenem-Resistant Acinetobacter Baumannii

A Oliva, S Garzoli, M De Angelis, C Marzuillo, V Vullo… - Molecules, 2019 - mdpi.com
Carbapenem-resistant Acinetobacter baumannii (CR-Ab) infections are associated with high
morbidity and mortality. The aim of the study was to evaluate the in-vitro activity of different …

Synergistic activities of colistin combinations with meropenem, sulbactam, minocycline, disodium fosfomycin, or vancomycin against different clones of carbapenem …

A Sertcelik, I Baran, E Akinci, I Mumcuoglu… - Microbial Drug …, 2020 - liebertpub.com
Aims: Colistin became the primary treatment option for Acinetobacters that had developed a
high rate of resistance to carbapenems which were the first-line therapy in the past, and now …

Enhanced bacterial killing with colistin/sulbactam combination against carbapenem-resistant Acinetobacter baumannii

X Bian, X Liu, M Feng, PJ Bergen, J Li, Y Chen… - International Journal of …, 2021 - Elsevier
Aims: Polymyxin-based combination therapy is often used to treat carbapenem-resistant
Acinetobacter baumannii (A. baumannii) infections. Although sulbactam is intrinsically active …

In vitro antimicrobial synergy of colistin with rifampicin and carbapenems against colistin-resistant Acinetobacter baumannii clinical isolates

DJ Hong, JO Kim, H Lee, EJ Yoon, SH Jeong… - … and infectious disease, 2016 - Elsevier
Increased use of colistin in a clinical setting had resulted in the emergence of colistin-
resistant (CoR) Acinetobacter baumannii. Combination therapy has been studied as a new …

In Vitro Synergistic Activity of Antimicrobial Agents in Combination against Clinical Isolates of Colistin-Resistant Acinetobacter baumannii

S Bae, MC Kim, SJ Park, HS Kim, H Sung… - Antimicrobial agents …, 2016 - Am Soc Microbiol
Emerging resistance to colistin in clinical Acinetobacter baumannii isolates is of growing
concern. Since current treatment options for these strains are extremely limited, we …

In vitro synergistic activity of colistin with tigecycline or β-lactam antibiotic/β-lactamase inhibitor combinations against carbapenem-resistant Acinetobacter baumannii

I Karaoglan, Y Zer, VK Bosnak… - Journal of …, 2013 - journals.sagepub.com
Objective Nosocomial infection caused by carbapenem-resistant Acinetobacter baumannii is
a worldwide problem and treatment options remain controversial. This study investigated the …

In Vitro Synergy of Colistin in Combination with Meropenem or Tigecycline against Carbapenem-Resistant Acinetobacter baumannii

JC Abdul-Mutakabbir, J Yim, L Nguyen, PT Maassen… - Antibiotics, 2021 - mdpi.com
Acinetobacter baumannii is currently classified as one of six pathogens that contribute to
increased patient mortality. Thus, exploratory studies navigating alternative treatment …

In vitro synergy of polymyxins with other antibiotics for Acinetobacter baumannii: a systematic review and meta-analysis

W Ni, X Shao, X Di, J Cui, R Wang, Y Liu - International journal of …, 2015 - Elsevier
In order to provide preliminary guidance for rational antibiotic combination therapy in the
clinic, a systematic review and meta-analysis was performed to evaluate the in vitro …

[PDF][PDF] Synergic bactericidal activity of novel antibiotic combinations against extreme drug resistant Pseudomonas aeruginosa and Acinetobacter baumannii

E Aboulmagd, AA Alsultan - African Journal of …, 2014 - pdfs.semanticscholar.org
The emergence of extreme drug resistant (XDR) Pseudomonas aeruginosa and
Acinetobacter baumannii represent a major problem in health care settings. Colistin is the …