The present and the future of degradable dendrimers and derivatives in theranostics
Interest in dendrimer-based nanomedicines has been growing recently, as it is possible to
precisely manipulate the molecular weight, chemical composition, and surface functionality …
precisely manipulate the molecular weight, chemical composition, and surface functionality …
Preclinical studies of dendrimer prodrugs
C Kojima - Expert Opinion on Drug Metabolism & Toxicology, 2015 - Taylor & Francis
Introduction: Dendrimers are synthetic macromolecules with well-defined structures bearing
a wide variety of functional groups on their periphery. These groups can be used to …
a wide variety of functional groups on their periphery. These groups can be used to …
Dendrimers as drug delivery systems
G Kyriazis, P Papaioannidou - Front. Pharmacol. Conference Abstract …, 2010 - frontiersin.org
Dendrimers are a unique class of repeatedly branched polymeric nanomolecules, with a
tremendous potential in applications involving imaging, diagnostics and targeted therapy. As …
tremendous potential in applications involving imaging, diagnostics and targeted therapy. As …
Dendrimers in medicine: therapeutic concepts and pharmaceutical challenges
Dendrimers are three-dimensional macromolecular structures originating from a central core
molecule and surrounded by successive addition of branching layers (generation). These …
molecule and surrounded by successive addition of branching layers (generation). These …
Multivalent dendritic architectures for theranostics
S Reichert, M Calderón, K Licha, R Haag - … Nanoparticles for Drug …, 2012 - Springer
For the past few years, molecular imaging and targeted drug delivery have been playing an
important role toward personalized medicine. In designing and fabricating of multifunctional …
important role toward personalized medicine. In designing and fabricating of multifunctional …
Dendrimer-based nanosized MRI contrast agents
H Kobayashi, MW Brechbiel - Current pharmaceutical …, 2004 - ingentaconnect.com
Paramagnetic metals can induce T1 shortening by interaction with free water molecules.
Two metal ions, Gadolinium and Manganese, are currently available for human use …
Two metal ions, Gadolinium and Manganese, are currently available for human use …
Dendrimers as multi-purpose nanodevices for oncology drug delivery and diagnostic imaging
DA Tomalia, LA Reyna, S Svenson - 2007 - portlandpress.com
Dendrimers are routinely synthesized as tuneable nanostructures that may be designed and
regulated as a function of their size, shape, surface chemistry and interior void space. They …
regulated as a function of their size, shape, surface chemistry and interior void space. They …
[HTML][HTML] Diagnostic and therapeutic applications of smart nanocomposite dendrimers
Dendrimers are three dimensional, multifunctional polymeric structures which are composed
of a core and branches emanating from these structures, resembling a tree. Here, we review …
of a core and branches emanating from these structures, resembling a tree. Here, we review …
Dendrimer‐Based Medical Nanodevices for Magnetic Resonance Imaging Applications
H Cai, M Shen, X Shi - … Drug Delivery Systems: From Theory to …, 2012 - Wiley Online Library
Magnetic resonance (MR) imaging is a powerful, noninvasive imaging technique for disease
diagnosis. Its advantages include a high spatial resolution, a nonionizing radiation source …
diagnosis. Its advantages include a high spatial resolution, a nonionizing radiation source …
An overview of dendrimers and their biomedical applications
The versatility of the terminal functionality and the flexibility toward structural modification
allow a broad range of utilization of dendrimers. Since their discovery, the exploitation of …
allow a broad range of utilization of dendrimers. Since their discovery, the exploitation of …