Immunogenicity and safety of a tri-antigenic versus a mono-antigenic hepatitis B vaccine in adults (PROTECT): a randomised, double-blind, phase 3 trial

T Vesikari, JM Langley, N Segall, BJ Ward… - The Lancet Infectious …, 2021 - thelancet.com
Background The seroprotection rate (SPR) of hepatitis B vaccination in adults is suboptimal.
The aim of this study was to compare the SPR of a tri-antigenic hepatitis B vaccine (TAV) …

Immunogenicity and safety of a 3-antigen hepatitis B vaccine vs a single-antigen hepatitis B vaccine: a phase 3 randomized clinical trial

T Vesikari, A Finn, P Van Damme… - JAMA network …, 2021 - jamanetwork.com
Importance There is a need for improved immunogenicity of hepatitis B virus (HBV) vaccines
among young adults with risk of infection. Objectives To demonstrate manufacturing …

[PDF][PDF] Adult hepatitis B vaccination using a novel triple antigen recombinant vaccine

MD Young, DL Schneider, AJ Zuckerman, W Du… - …, 2001 - Wiley Online Library
Present hepatitis B vaccines use multidose prolonged regimens, which even healthcare
workers at risk do not always complete. Moreover, when vaccination is completed there …

Comparison of a triple antigen and a single antigen recombinant vaccine for adult hepatitis B vaccination

MD Young, WM Gooch III, AJ Zuckerman… - Journal of medical …, 2001 - Wiley Online Library
Hepatitis B and its sequelae are a major public health problem. Vaccines have been
available for almost 20 years; however the disease still remains a global problem. Many …

Five years follow-up following two or three doses of a hepatitis B vaccine in adolescents aged 11-15 years: a randomised controlled study

P Van Damme, A Moiseeva, I Marichev… - BMC infectious …, 2010 - Springer
Background The standard three-dose schedule of hepatitis B vaccines is frequently not
completed, especially in adolescents. A primary study has confirmed the equivalence of a …

Antibody-response to three recombinant hepatitis B vaccines: comparative evaluation of multicenter travel-clinic based experience

P Rendi-Wagner, M Kundi, H Stemberger… - Vaccine, 2001 - Elsevier
The immunogenicity of three currently used hepatitis B vaccines was compared in an
unselected study population in an every day travel clinical setting. Five hundred and …

Excellent response rate to a double dose of the combined hepatitis A and B vaccine in previous nonresponders to hepatitis B vaccine

K Cardell, B Åkerlind, M Sällberg… - The Journal of infectious …, 2008 - academic.oup.com
Background. Hepatitis B vaccine has been shown to be highly efficient in preventing
hepatitis B. However, 5%–10% of individuals fail to develop protective levels (≥ 10 mIU/mL) …

Hepatitis B vaccines: WHO position paper, July 2017–Recommendations

World Health Organization - Vaccine, 2019 - Elsevier
This article presents the World Health Organization's (WHO) recommendations on the use of
hepatitis B vaccines excerpted from the Hepatitis B vaccines: WHO position paper, July …

Long-term immunogenicity of hepatitis B vaccination and policy for booster: an Italian multicentre study

AR Zanetti, A Mariano, L Romanò, R D'Amelio… - The Lancet, 2005 - thelancet.com
Background Universal anti-hepatitis-B vaccination of infants and adolescents was
implemented in Italy in 1991. We undertook a multicentre study in previously vaccinated …

Comparison of four recombinant hepatitis B vaccines applied on an accelerated schedule in healthy adults

F Hernández-Bernal, A Aguilar-Betancourt… - Human …, 2011 - Taylor & Francis
A post-marketing, double blind, randomised, controlled clinical trial to assess the
immunogenicity and safety profiles of four commercially available recombinant hepatitis B …