Deficits in cerebellum-dependent learning and cerebellar morphology in male and female BTBR autism model mice

EA Kiffmeyer, JA Cosgrove, JK Siganos, HE Bien… - NeuroSci, 2022 - mdpi.com
Recently, there has been increased interest in the role of the cerebellum in autism spectrum
disorder (ASD). To better understand the pathophysiological role of the cerebellum in ASD, it …

[HTML][HTML] Impact of cerebellar-specific genetic and circuit manipulations on the behavioral phenotype and cerebellar physiology in murine autism models

L Wahl, I Serra, A Badura - Current Opinion in Behavioral Sciences, 2024 - Elsevier
Highlights•Stereotyped behavior has large variability within cerebellar-specific genetic
models.•Cerebellar manipulations show region-specific and time-dependent effects on …

[HTML][HTML] The role of cerebellar circuitry alterations in the pathophysiology of autism spectrum disorders

MW Mosconi, Z Wang, LM Schmitt, P Tsai… - Frontiers in …, 2015 - frontiersin.org
The cerebellum has been repeatedly implicated in gene expression, rodent model and post-
mortem studies of autism spectrum disorder (ASD). How cellular and molecular anomalies of …

Abnormal cerebellar development is involved in dystonia-like behaviors and motor dysfunction of autistic BTBR mice

R Xiao, H Zhong, X Li, Y Ma, R Zhang… - Frontiers in Cell and …, 2020 - frontiersin.org
Motor control and learning impairments are common complications in individuals with
autism spectrum disorder (ASD). Abnormal cerebellar development during critical phases …

Autism spectrum disorder and the cerebellum

EBE Becker, CJ Stoodley - International review of neurobiology, 2013 - Elsevier
The cerebellum has been long known for its importance in motor learning and coordination.
Recently, anatomical, clinical, and neuroimaging studies strongly suggest that the …

Cerebellar involvement in autism and ADHD

MMK Bruchhage, MP Bucci, EBE Becker - Handbook of clinical neurology, 2018 - Elsevier
The cerebellum has long been known for its importance in motor learning and coordination.
However, increasing evidence supports a role for the cerebellum in cognition and emotion …

Targeting inhibitory cerebellar circuitry to alleviate behavioral deficits in a mouse model for studying idiopathic autism

OY Chao, E Marron Fernandez de Velasco… - …, 2020 - nature.com
Autism spectrum disorder (ASD) encompasses wide-ranging neuropsychiatric symptoms
with unclear etiology. Although the cerebellum is a key region implicated in ASD, it remains …

Regulation of autism-relevant behaviors by cerebellar–prefrontal cortical circuits

E Kelly, F Meng, H Fujita, F Morgado, Y Kazemi… - Nature …, 2020 - nature.com
Cerebellar dysfunction has been demonstrated in autism spectrum disorders (ASDs);
however, the circuits underlying cerebellar contributions to ASD-relevant behaviors remain …

[HTML][HTML] Cerebellar structure and function in autism spectrum disorder

BF Bloomer, JJ Morales, AR Bolbecker… - Journal of psychiatry …, 2022 - ncbi.nlm.nih.gov
Autism spectrum disorder (ASD) is a heterogeneous neurodevelopmental condition
characterized by early-onset repetitive behaviors, restricted interests, sensory and motor …

Altered cerebellar connectivity in autism and cerebellar-mediated rescue of autism-related behaviors in mice

CJ Stoodley, AM D'Mello, J Ellegood… - Nature …, 2017 - nature.com
Cerebellar abnormalities, particularly in Right Crus I (RCrusI), are consistently reported in
autism spectrum disorders (ASD). Although RCrusI is functionally connected with ASD …