[HTML][HTML] Serum ceramide species are associated with liver cirrhosis and viral genotype in patients with hepatitis C infection

M Höring, G Peschel, J Grimm, S Krautbauer… - International journal of …, 2022 - mdpi.com
Hepatitis C virus (HCV) infection affects ceramide metabolism, and, here, we have evaluated
associations of eight serum ceramide species with viral load, viral genotype, and disease …

Elevated plasma sphingomyelin (d18: 1/22: 0) is closely related to hepatic steatosis in patients with chronic hepatitis C virus infection

JF Li, F Qu, SJ Zheng, HL Wu, M Liu, S Liu… - European journal of …, 2014 - Springer
Hepatic steatosis affects disease progression in patients with chronic hepatitis C virus (HCV)
infection. We investigated the plasma sphingolipid profile in patients with chronic hepatitis C …

[HTML][HTML] Ceramide content in liver increases along with insulin resistance in obese patients

H Razak Hady, AU Błachnio-Zabielska… - Journal of clinical …, 2019 - mdpi.com
The liver plays a central role in the glucose and lipid metabolism. Studies performed on
animal models have shown an important role of lipid accumulation in the induction of insulin …

[HTML][HTML] Plasma ceramides are associated with MRI-based liver fat content but not with noninvasive scores of liver fibrosis in patients with type 2 diabetes

D Denimal, S Béland-Bonenfant… - Cardiovascular …, 2023 - Springer
Background There is growing evidence that ceramides play a significant role in the onset
and progression of non-alcoholic fatty liver disease (NAFLD), a highly prevalent condition in …

[HTML][HTML] Low serum levels of (dihydro-) ceramides reflect liver graft dysfunction in a real-world cohort of patients post liver transplantation

VT Mücke, J Gerharz, K Jakobi, D Thomas… - International journal of …, 2018 - mdpi.com
Patients after orthopic liver transplantation (OLT) are at risk of developing graft dysfunction.
Sphingolipids (SL's) have been identified to play a pivotal role in the regulation of …

Ceramide concentrations in liver, plasma, and very low‐density lipoproteins of humans with severe obesity

KA Lytle, JO Chung, NC Bush, JM Triay, MD Jensen - Lipids, 2023 - Wiley Online Library
We investigated the relationships between ceramide species concentrations in liver, plasma
and very low‐density lipoproteins (VLDL) particles of humans with obesity as well as the …

[HTML][HTML] Circulating ceramide: a new cardiometabolic biomarker in patients with comorbid acute coronary syndrome and type 2 diabetes mellitus

R Cao, Z Fang, S Li, M Xu, J Zhang, D Han… - Frontiers in …, 2020 - frontiersin.org
Aims This study investigated the association of circulating ceramides in patients with
comorbid acute coronary syndrome and type 2 diabetes mellitus (ACS-DM). Methods A total …

Association between plasmatic ceramides profile and AST/ALT ratio: C14: 0 ceramide as predictor of hepatic steatosis in adolescents independently of obesity

J Maldonado-Hernández… - Canadian Journal of …, 2017 - Wiley Online Library
Objective. To assess the association between plasma ceramides and hepatic steatosis (HS)
in adolescents, independently of obesity. Materials and Methods. Ninety‐four adolescents …

[HTML][HTML] Ceramide as a mediator of non-alcoholic fatty liver disease and associated atherosclerosis

T Kasumov, L Li, M Li, K Gulshan, JP Kirwan, X Liu… - PloS one, 2015 - journals.plos.org
Cardiovascular disease (CVD) is a serious comorbidity in nonalcoholic fatty liver disease
(NAFLD). Since plasma ceramides are increased in NAFLD and sphingomyelin, a ceramide …

Associations between plasma ceramides and mortality in patients with coronary artery disease

Q Li, X Wang, J Pang, Y Zhang, H Zhang, Z Xu, Q Chen… - Atherosclerosis, 2020 - Elsevier
Background and aims The relationship between ceramides and the risk of mortality among
patients with coronary artery disease (CAD) is currently relatively sparse. This prospective …