Abstract Neuromyelitis Optica and Multiple Sclerosis are idiopathic inflammatory
demyelinating diseases of the central nervous system that currently are considered distinct …

Background To establish whether or not multiple sclerosis (MS) and neuromyelitis optica
(NMO) are different pathological entities, we wondered whether MS patients and NMO …

Background: Association of the HLA-DRB1* 1501 allele with multiple sclerosis is well
established, but its association with neuromyelitis optica has only been evaluated in small …

Background: Neuromyelitis optica (NMO) is a disease with autoimmune characteristics. A
genetic autoimmune dependency for NMO has not been clarified in detail. Objective: To …

Until recently, neuromyelitis optica (NMO) was considered to be a sub-type of multiple
sclerosis (MS), which has a strong predilection for Caucasian populations, whereas NMO is …

Background: Despite similarities, neuromyelitis optica (NMO) can be distinguished from
multiple sclerosis (MS) by clinical, radiological and serological findings. Objective: This case …

Objective To identify genetic factors associated with susceptibility to and clinical features of
neuromyelitis optica spectrum disorders (NMOSD). Methods Genome‐wide single …

Variations in the geographic distribution of multiple sclerosis (MS) and neuromyelitis optica
(NMO) suggest a role for possible genetic and environmental influences in the …

Neuromyelitis optica spectrum disorders (NMOSD) comprise a variety of disorders being
described by optic neuritis and myelitis. This disorder is mostly observed in sporadic form …

Results In the Spanish cohort, NMO was associated with increased frequency of DRB1* 10
allele compared with MS (odds ratio, OR= 15.1; 95% confidence interval, 95% CI= 3.26 …