Integration of in silico and in vitro analysis of gliotoxin production reveals a narrow range of producing fungal species
S Redrado, P Esteban, MP Domingo, C Lopez… - Journal of Fungi, 2022 - mdpi.com
Gliotoxin is a fungal secondary metabolite with impact on health and agriculture since it
might act as virulence factor and contaminate human and animal food. Homologous …
might act as virulence factor and contaminate human and animal food. Homologous …
[HTML][HTML] Towards understanding the gliotoxin detoxification mechanism: in vivo thiomethylation protects yeast from gliotoxin cytotoxicity
Gliotoxin (GT) is a mycotoxin produced by some species of ascomycete fungi including the
opportunistic human pathogen Aspergillus fumigatus. In order to produce GT the host …
opportunistic human pathogen Aspergillus fumigatus. In order to produce GT the host …
Culture conditions for zinc-and pH-regulated gene expression studies in Aspergillus fumigatus
In Aspergillus fumigatus, the regulation of zinc homeostasis is strongly influenced by
environmental pH. Thus, the study of zinc-regulated gene expression in A. fumigatus …
environmental pH. Thus, the study of zinc-regulated gene expression in A. fumigatus …
Fungal G-protein-coupled receptors: a promising mediator of the impact of extracellular signals on biosynthesis of ochratoxin A
J Gao, X Xu, K Huang, Z Liang - Frontiers in Microbiology, 2021 - frontiersin.org
G-protein-coupled receptors (GPCRs) are transmembrane receptors involved in transducing
signals from the external environment inside the cell, which enables fungi to coordinate cell …
signals from the external environment inside the cell, which enables fungi to coordinate cell …
Perturbations in small molecule synthesis uncovers an iron-responsive secondary metabolite network in Aspergillus fumigatus
P Wiemann, BE Lechner, JA Baccile, TA Velk… - Frontiers in …, 2014 - frontiersin.org
Iron plays a critical role in survival and virulence of the opportunistic pathogen Aspergillus
fumigatus. Two transcription factors, the GATA-factor SreA and the bZip-factor HapX …
fumigatus. Two transcription factors, the GATA-factor SreA and the bZip-factor HapX …
Aspergillus fumigatus mitogen-activated protein kinase MpkA is involved in gliotoxin production and self-protection
P Alves de Castro, C Figueiredo Pinzan… - Nature …, 2024 - nature.com
Aspergillus fumigatus is a saprophytic fungus that can cause a variety of human diseases
known as aspergillosis. Mycotoxin gliotoxin (GT) production is important for its virulence and …
known as aspergillosis. Mycotoxin gliotoxin (GT) production is important for its virulence and …
G‐protein signalling mediates differential production of toxic secondary metabolites
A Tag, J Hicks, G Garifullina, C Ake Jr… - Molecular …, 2000 - Wiley Online Library
Filamentous fungi elaborate a complex array of secondary metabolites, including antibiotics
and mycotoxins. As many of these compounds pose significant economic and health …
and mycotoxins. As many of these compounds pose significant economic and health …
A Proteomic Approach to Investigating Gene Cluster Expression and Secondary Metabolite Functionality in Aspergillus fumigatus
A combined proteomics and metabolomics approach was utilised to advance the
identification and characterisation of secondary metabolites in Aspergillus fumigatus. Here …
identification and characterisation of secondary metabolites in Aspergillus fumigatus. Here …
Increased production of gliotoxin is related to the formation of biofilm by Aspergillus fumigatus: an immunological approach
Gliotoxin (GT) belongs to the epipolythiodioxopiperazine class of toxins secreted from
certain fungi including Aspergillus fumigatus, which is the most prolific producer of this …
certain fungi including Aspergillus fumigatus, which is the most prolific producer of this …
The Transcriptome Response to Azole Compounds in Aspergillus fumigatus Shows Differential Gene Expression across Pathways Essential for Azole Resistance …
MWJ Hokken, JPM Coolen, H Steenbreker, J Zoll… - Journal of Fungi, 2023 - mdpi.com
The opportunistic pathogen Aspergillus fumigatus is found on all continents and thrives in
soil and agricultural environments. Its ability to readily adapt to novel environments and to …
soil and agricultural environments. Its ability to readily adapt to novel environments and to …