Background: The relationship of TP53 codons 72, IVS3 16 bp, and IVS6+ 62A> G
polymorphisms with breast cancer (BC) risk has been analyzed in seventeen published …

The association of polymorphisms of tumor suppressor gene TP53 with breast cancer has
widely been reported; however, the results are inconsistent. Here, we selected three …

Conflicting data have been published as to the possible association between polymorphism
in codon 72 of the TP53 tumor suppressor gene and the risk of developing breast cancer. In …

Background Previously, TP53 codon 72 polymorphisms have been implicated as risk factors
for various cancers. A number of studies have conducted on the association of TP53 codon …

This study was conducted in order to investigate the implications of the R72P polymorphism
in the TP53 gene in breast cancer risk. The enlightenment of this matter might provide a …

Abstract p53 is a tumor suppressor gene and plays an important role in the etiology of breast
cancer. However, studies on the association between p53 polymorphisms and breast cancer …

Background Many studies have demonstrated that the genetic variants of tumor suppressor
gene TP53 contribute to the prediction of breast cancer risk. However, most of them focused …

Background: A common Arg/Pro polymorphism at codon 72 of the TP53 gene has been
investigated as a risk factor for cancer in different populations. So far, the results have been …

Background: Breast cancer is the leading cause of cancer deaths among women. Early-
onset breast cancer is well recognized as it clinically differs from old-age diagnosed breast …

Variations in the TP53 gene have been suggested to play a role in many cancers, including
breast. We previously observed an association between TP53 haplotypes based on four …