We recently reported that Cx43 expression and gap junction intercellular communication
(GJIC) between acute leukemic bone marrow stromal cells (BMSCs) were deficient, which …

Gap junction intercellular communication (GJIC) among bone marrow stromal cells (BMSCs)
most frequently occurs through a channel composed of connexin43 (Cx43). Dysregulation of …

Abstract Connexin 43 (Cx43) induced apoptosis has been reported in solid tumors, but the
effect of Cx43 expressed by bone marrow stromal cells (BMSC) in leukemia has not been …

The bone marrow (BM) niche impacts the progression of acute myeloid leukemia (AML) by
favoring the chemoresistance of AML cells. Intimate interactions between leukemic cells and …

The role of proinflammatory cytokines secreted by the bone marrow mesenchymal stromal
cells (BM‐MSCs) in the progression of acute myeloid leukemia (AML) is poorly understood …

Normal and leukemic blood cell progenitors depend upon the bone marrow (BM) stroma
with which they communicate through soluble and membrane-anchored mediators …

This study investigated the effects of human bone marrow fibroblastoid stromal cell line
(HFCL) on the proliferation, differentiation and chemosensitivity of acute myeloid leukemia …

Cx43 expressed on bone marrow stromal cells plays an essential role in multiple myeloma
cell survival and drug resistance Page 1 Basic research Corresponding author: Prof …

Objectives: Multipotent mesenchymal stromal cells (MSCs) play a central role within the
bone marrow (BM) niche, supporting hematopoiesis via soluble factors like cytokines and …

Purpose To investigate the role of the CXCR4/CXCL12 axis in chemotherapy resistance in
refractory/relapsed (R/R) ALL patients. Methods CXCR4 expression on ALL cells from newly …