Study on the effect of macrophages on vascular endothelium in mice with different TCM syndromes of dyslipidemia and its biological basis based on RNA-seq …
J Chen, C Ye, Z Yang, T Wang, B Xu, P Li… - Frontiers in …, 2021 - frontiersin.org
Background:“Treating the same disease with different methods” is a Traditional Chinese
medicine (TCM) therapeutic concept suggesting that, while patients may be diagnosed with …
medicine (TCM) therapeutic concept suggesting that, while patients may be diagnosed with …
Exploring the “gene–protein–metabolite” network of coronary heart disease with phlegm and blood stasis syndrome by integrated multi-omics strategy
G Yang, S Zhou, H He, Z Shen, Y Liu, J Hu… - Frontiers in …, 2022 - frontiersin.org
Background: According to the theory of traditional Chinese medicine, phlegm and blood
stasis (PBS) is the pathological basis for coronary heart disease (CHD). This study aimed to …
stasis (PBS) is the pathological basis for coronary heart disease (CHD). This study aimed to …
Effects of Atherogenic Factors on Endothelial Cells: Bioinformatics Analysis of Differentially Expressed Genes and Signaling Pathways
S Kotlyarov - Biomedicines, 2023 - mdpi.com
(1) Background: Atherosclerosis is a serious medical condition associated with high
morbidity and mortality rates. It develops over many years as a complex chain of events in …
morbidity and mortality rates. It develops over many years as a complex chain of events in …
[HTML][HTML] Mechanisms of Yangxin Tongmai Formula for blood stasis syndrome in coronary heart disease rats based on untargeted plasma metabolomics and intestinal …
L Yinxing, C Zijun, W Yiqin, C Xihua, L Jie… - Digital Chinese …, 2023 - Elsevier
Objective To investigate the correlations between intestinal flora, plasma metabolites, and
blood stasis syndrome in coronary heart disease (CHD), and the mechanisms of Yangxin …
blood stasis syndrome in coronary heart disease (CHD), and the mechanisms of Yangxin …
Comparative transcriptomic analysis revealed novel potential therapeutic targets of traditional Chinese medicine (Pinggan-Qianyang decoction) on vascular …
J Yao, C Zhang, Y Yang, X Fang, Q Chen, G Zhong - Chinese medicine, 2021 - Springer
Background Both experimental and clinical studies have revealed satisfactory effects with
the traditional Chinese formula Pinggan Qianyang decoction (PGQYD) for improving …
the traditional Chinese formula Pinggan Qianyang decoction (PGQYD) for improving …
Exploring the protective effect of Modified Xiaochaihu Decoction against hepatic steatosis and inflammation by network pharmacology and validation in ageing rats
S Gao, T Wang, XK Huang, Y Jin, Y Xu, Y Xi, J Zhang… - Chinese Medicine, 2020 - Springer
Background Based on therapy with syndrome differentiation and clinical studies on
Xiaochaihu decoction (XCHD), we hypothesize that Modified Xiaochaihu Decoction (MXD) …
Xiaochaihu decoction (XCHD), we hypothesize that Modified Xiaochaihu Decoction (MXD) …
Role of dysregulated macrophage subpopulation ratios and functional changes in the development of coronary atherosclerosis
Y Xiao, X Huang, Y Xia, M Ding, A Li… - The Journal of Gene …, 2024 - Wiley Online Library
Coronary heart disease is one of the most significant risk factors affecting human health
worldwide. Its pathogenesis is intricate, with atherosclerosis being widely regarded as the …
worldwide. Its pathogenesis is intricate, with atherosclerosis being widely regarded as the …
[HTML][HTML] A combined transcriptomics and proteomics approach to reveal the mechanism of AEE relieving hyperlipidemia in ApoE-/-mice
XR Lu, Q Tao, Z Qin, XW Liu, SH Li, LX Bai… - Biomedicine & …, 2024 - Elsevier
Hyperlipidemia caused by abnormal lipid metabolism has reached epidemic proportions.
This phenomenon is also common in companion animals. Previous studies showed that …
This phenomenon is also common in companion animals. Previous studies showed that …
Exploring and verifying the mechanism and targets of shenqi pill in the treatment of nonalcoholic steatohepatitis via network pharmacology and experiments
B He, Z Chen, Y Nie, M Luo, S Xu… - Journal of Immunology …, 2022 - Wiley Online Library
Shenqi pill (SQP), a famous traditional Chinese medicine (TCM) herbal formula derived from
Jinguiyaolue (Synopsis of Prescriptions of the Golden Chamber), has long been used to …
Jinguiyaolue (Synopsis of Prescriptions of the Golden Chamber), has long been used to …
[HTML][HTML] Identification of genes and pathways related to atherosclerosis comorbidity and depressive behavior via RNA-seq and bioinformation analysis in ApoE …
J Zhou, C Zhang, X Wu, Q Xie, L Li, Y Chen… - Annals of …, 2019 - ncbi.nlm.nih.gov
Background Depression is an independent risk factor for atherosclerosis (AS), which can
increase the risk of death and disability from AS. However, the mechanism of AS comorbidity …
increase the risk of death and disability from AS. However, the mechanism of AS comorbidity …