Preliminary report on the feasibility and efficacy of the modified Atkins diet for treatment of mild cognitive impairment and early Alzheimer's disease

J Brandt, A Buchholz, B Henry-Barron… - Journal of …, 2019 - content.iospress.com
Ketone bodies, the products of fat metabolism, are a source of energy for the brain and are
available even when glucose supplies are inadequate (such as with severe carbohydrate …

Effects of a ketogenic and low‐fat diet on the human metabolome, microbiome, and foodome in adults at risk for Alzheimer's disease

AH Dilmore, C Martino, BJ Neth, KA West… - Alzheimer's & …, 2023 - Wiley Online Library
INTRODUCTION The ketogenic diet (KD) is an intriguing therapeutic candidate for
Alzheimer's disease (AD) given its protective effects against metabolic dysregulation and …

[HTML][HTML] The efficacy of ketogenic therapies in the clinical management of people with neurodegenerative disease: a systematic review

LS Dewsbury, CK Lim, GZ Steiner - Advances in Nutrition, 2021 - Elsevier
Ketone bodies have potential disease-modifying activity that represent a novel therapeutic
approach for neurodegenerative diseases (NDD). The aim of this systematic review was to …

The effect of the ketogenic diet on the therapy of neurodegenerative diseases and its impact on improving cognitive functions

K Grochowska, A Przeliorz - Dementia and geriatric cognitive disorders …, 2022 - karger.com
The ketogenic diet (KD) is a high-fat and low-carbohydrate diet with controlled amounts of
protein. The use of drastic caloric restriction or ultralow-carbohydrate diets increases the …

Medium Chain Triglycerides induce mild ketosis and may improve cognition in Alzheimer's disease. A systematic review and meta-analysis of human studies

KI Avgerinos, JM Egan, MP Mattson… - Ageing research …, 2020 - Elsevier
Introduction/aim The brain in Alzheimer's disease shows glucose hypometabolism but may
utilize ketones for energy production. Ketone levels can potentially be boosted through oral …

The therapeutic role of ketogenic diet in neurological disorders

D Pietrzak, K Kasperek, P Rękawek… - Nutrients, 2022 - mdpi.com
The ketogenic diet (KD) is a high-fat, low-carbohydrate and adequate-protein diet that has
gained popularity in recent years in the context of neurological diseases (NDs). The …

Enhanced cerebral bioenergetics with dietary ketosis in mild cognitive impairment

R Krikorian, EL Boespflug, JA Dudley… - Nutrition and …, 2014 - content.iospress.com
BACKGROUND: Metabolic disturbance is associated with risk for neurodegeneration, and
cerebral glucose hypometabolism is prominent in Alzheimer's disease (AD). Ketone …

Modified ketogenic diet is associated with improved cerebrospinal fluid biomarker profile, cerebral perfusion, and cerebral ketone body uptake in older adults at risk for …

BJ Neth, A Mintz, C Whitlow, Y Jung, KS Sai… - Neurobiology of …, 2020 - Elsevier
There is currently no established therapy to treat or prevent Alzheimer's disease. The
ketogenic diet supplies an alternative cerebral metabolic fuel, with potential neuroprotective …

A ketogenic diet reduces amyloid beta 40 and 42 in a mouse model of Alzheimer's disease

I Van der Auwera, S Wera, F Van Leuven… - Nutrition & …, 2005 - Springer
Background Alzheimer's disease (AD) is a progressive neurodegenerative disorder that
primarily strikes the elderly. Studies in both humans and animal models have linked the …

The impact of ketogenic diet on the onset and progression of multiple sclerosis

JD Brockhoff, S Bereswill… - European Journal of …, 2023 - akjournals.com
Multiple sclerosis (MS) is a chronic autoimmune disease of the central nervous system
(CNS) characterized by inflammation and neurodegeneration. Current research suggests …