Serum and CSF metabolomics analysis shows Mediterranean Ketogenic Diet mitigates risk factors of Alzheimer's disease

A Schweickart, R Batra, BJ Neth, C Martino… - NPJ Metabolic Health …, 2024 - nature.com
Alzheimer's disease (AD) is influenced by a variety of modifiable risk factors, including a
person's dietary habits. While the ketogenic diet (KD) holds promise in reducing metabolic …

A Root in Synapsis and the Other One in the Gut Microbiome-Brain Axis: Are the Two Poles of Ketogenic Diet Enough to Challenge Glioblastoma?

L Montella, F Sarno, L Altucci, V Cioffi, L Sigona… - Frontiers in …, 2021 - frontiersin.org
Glioblastoma is the most frequent and aggressive brain cancer in adults. While precision
medicine in oncology has produced remarkable progress in several malignancies, treatment …

Ketogenic medium chain triglycerides increase brain energy metabolism in Alzheimer's disease

E Croteau, CA Castellano, MA Richard… - Journal of …, 2018 - content.iospress.com
Background: In Alzheimer's disease (AD), it is unknown whether the brain can utilize
additional ketones as fuel when they are derived from a medium chain triglyceride (MCT) …

A new way to produce hyperketonemia: use of ketone ester in a case of Alzheimer's disease

MT Newport, TB VanItallie, Y Kashiwaya, MT King… - Alzheimer's & …, 2015 - Elsevier
Background Providing ketone bodies to the brain can bypass metabolic blocks to glucose
utilization and improve function in energy-starved neurons. For this, plasma ketones must be …

[HTML][HTML] Ketogenic diets for adult neurological disorders

TJW McDonald, MC Cervenka - Neurotherapeutics, 2018 - Elsevier
The current review highlights the evidence supporting the use of ketogenic diet therapies in
the management of a growing number of neurological disorders in adults. An overview of the …

A ketogenic diet improves cognition and has biochemical effects in prefrontal cortex that are dissociable from hippocampus

AR Hernandez, CM Hernandez, K Campos… - Frontiers in aging …, 2018 - frontiersin.org
Age-related cognitive decline has been linked to a diverse set of neurobiological
mechanisms, including bidirectional changes in proteins critical for neuron function …

Dietary patterns and Alzheimer's disease: an updated review linking nutrition to neuroscience

I Ellouze, J Sheffler, R Nagpal, B Arjmandi - Nutrients, 2023 - mdpi.com
Alzheimer's disease (AD) is a growing concern for the aging population worldwide. With no
current cure or reliable treatments available for AD, prevention is an important and growing …

Nutrition-based approaches in clinical trials targeting cognitive function: highlights of the CTAD 2020

KV Giudici - The Journal of Prevention of Alzheimer's Disease, 2021 - Springer
(CTAD) 2020 conference was the stage for researchers from all over the world to present
their recent and ongoing research focused on potential Alzheimer's disease (AD) treatments …

Study of the ketogenic agent AC-1202 in mild to moderate Alzheimer's disease: a randomized, double-blind, placebo-controlled, multicenter trial

ST Henderson, JL Vogel, LJ Barr, F Garvin… - Nutrition & …, 2009 - Springer
Background Alzheimer's disease (AD) is characterized by early and region-specific declines
in cerebral glucose metabolism. Ketone bodies are produced by the body during glucose …

[PDF][PDF] Ketogenic diet: Biochemistry, weight loss and clinical applications

A Arnold, A Ali, N Kaka, P Kakodkar - Nutri. Food Sci. Int. J, 2020 - researchgate.net
The ketogenic diet (KD) has obtained immense popularity that stretches beyond its myriad of
clinical applications. KD provides a practical solution to attain body recompositing and meet …