Endothelial dysfunction is a common disorder of vascular homeostasis in hypertension
characterized by oxidative stress, malignant migration, inflammatory response, and active …

Angiotensin II (Ang II), a vasoactive factor in the renin–angiotensin–aldosterone system
(RAAS), can regulate vasoconstriction and promote multiple vascular diseases. In this study …

Oxidative stress and vascular inflammatory response are key mediators of endothelial
dysfunction that leads to cardiovascular diseases. A novel peptide, IRW, was previously …

Abstract Hyperactivity of the Renin-Angiotensin System (RAS) is a hallmark of hypertension.
Angiotensin II (AngII), the active component of RAS, not only promotes vasoconstriction but …

Vascular oxidative stress, inflammatory response, and proliferation are crucial mediators of
vascular dysfunction which contribute to the pathology of hypertension. A tripeptide, LRW …

Excessive proliferation, inflammation, oxidative stress, and migration induced by angiotensin
II (Ang II), occurring in vascular smooth muscle cells (VSMCs) during vascular remodelling …

The excessive accumulation of angiotensin II (Ang II) in the vascular microenvironment
promotes vascular dysfunction including vascular endothelial inflammation and remodeling …

An emerging inference is that vascular cells transfer their biological cargo to recipient cells
by secretion of extracellular vesicles (EVs). This study explored the effects of EVs produced …

Aim: A food-derived bioactive tripeptide, Val-Pro-Pro (VPP), has been shown to possess
angiotensin I-converting enzyme (ACE) inhibitory activity and foods containing such …

Vascular endothelial dysfunction is a vital pathological change in hypertension, which is
mainly caused by apoptosis and oxidative stress injury of vascular endothelial cells …