Hepatocellular carcinoma (HCC) is one of the major malignancies in the world. The
prognosis of HCC is poor, due to frequent intrahepatic metastasis and tumor recurrence …

P21-activated protein kinase (Pak1), a main downstream effector of small Rho GTPases,
plays an important role in the regulation of cell morphogenesis, motility, mitosis and …

Purpose: Hepatocellular carcinoma (HCC) is one of the most common malignant tumors.
The malignant biological behavior of HCC is closely related to epithelial-mesenchymal …

Abstract p21‐activated kinase 1 (Pak1), a serine/threonine kinase, has been implicated in
cytoskeletal remodelling, cell motility, apoptosis and transformation. However, the role of …

Background p21-activated protein kinase (PAK) 6 is a serine-threonine kinase belonging to
the PAK family. Previous studies have indicated that abnormal expressions of PAK1, PAK2 …

Aim: To investigate the roles of P21-activated kinase 5 (PAK5) in proliferation and
tumorigenicity of human hepatocellular carcinoma (HCC). Methods: HCC and matched …

Abstract P21‐activated kinase 5 (PAK5) is the recently identified member of the group B p21‐
activated kinase (PAK) family which are effectors of the small GTPase Cdc42 and Rac1 …

The p21-activated kinase (PAK) family of serine/threonine kinases plays an important role in
cell proliferation, survival and motility, as well as in cell transformation and tumor …

Abstract Background P21-activated kinase 4 (PAK4), an effector of the Rho family protein
Cdc42, is an important oncogene whose expression is increased in many human cancers …

Abstract P21-activated protein kinase1 (PAK1), a main downstream effector of small Rho
GTPases, Rac1, and Cdc42, plays an important role in the regulation of cell morphogenesis …