In prior work, Friends of Cancer Research convened multiple data partners to establish
standardized definitions for oncology real‐world end points derived from electronic health …

PURPOSE This study compared real-world end points extracted from the Cancer Analysis
System (CAS), a national cancer registry with linkage to national mortality and other health …

Background Evaluating cancer treatments in real-world data (RWD) requires informative
endpoints. Due to non-standardized data collection in RWD, it is unclear if and when …

Objective We expanded the previous assessment of a mortality variable suited for real‐world
evidence‐focused oncology research. Data source We used a nationwide electronic health …

Evaluating cancer treatments in real‐world data (RWD) requires informative endpoints. This
study replicated the atezolizumab and docetaxel arms of the OAK trial using RWD and …

PURPOSE This pilot study examined the ability to operationalize the collection of real-world
data to explore the potential use of real-world end points extracted from data from diverse …

Objectives This study aimed to demonstrate enhanced survival extrapolation methods using
electronic health record-derived real-world data (RWD). Methods The study population …

Recently, there has been a growing interest in using real-world data (RWD) to generate real-
world evidence that complements clinical trials. To quantify treatment effects, it is important …

PURPOSE Large, generalizable real-world data can enhance traditional clinical trial results.
The current study evaluates reliability, clinical relevance, and large-scale feasibility for a …

Background By understanding prognostic biomarkers, we gain insights into disease biology
and may improve design, conduct, and data analysis of clinical trials and real-world data. In …