The Neisseria gonorrhoeae f erric u ptake r egulator (Fur) protein controls expression of iron
homeostasis genes in response to intracellular iron levels. In this study, using transcriptome …

To ensure survival in the host, bacteria have evolved strategies to acquire the essential
element iron. In Neisseria gonorrhoeae, the ferric uptake regulator Fur regulates metabolism …

Like most microorganisms, Neisseria gonorrhoeae alters gene expression in response to
iron availability. The ferric uptake regulator Fur has been shown to be involved in controlling …

The ferric uptake regulatory protein, Fur, functions as a global regulatory protein of gene
transcription in the mucosal pathogen Neisseria gonorrhoeae. We have shown previously …

In this study, we have characterized the in vitro binding of Neisseria gonorrhoeae Fur to
several well-defined iron transport genes, as well as to additional genes involved in major …

Background For most pathogens, iron (Fe) homeostasis is crucial for maintenance within the
host and the ability to cause disease. The primary transcriptional regulator that controls …

To ensure survival, most bacteria must acquire iron, a resource that is sequestered by
mammalian hosts. Pathogenic bacteria have therefore evolved intricate systems to sense …

Iron is limiting in the human host, and bacterial pathogens respond to this environment by
regulating gene expression through the ferric uptake regulator protein (Fur). In vitro studies …

In this study we characterized a genetic locus that is predicted to encode one of the three
AraC-like regulators of Neisseria meningitidis, a homologue of MpeR of Neisseria …

Neisseria gonorrhoeae is one of the most prevalent sexually transmitted infections
worldwide. This obligate human pathogen has been extensively studied in vitro, where …