First-line nivolumab plus ipilimumab combined with two cycles of chemotherapy in patients with non-small-cell lung cancer (CheckMate 9LA): an international …

L Paz-Ares, TE Ciuleanu, M Cobo, M Schenker… - The Lancet …, 2021 - thelancet.com
Background First-line nivolumab plus ipilimumab has shown improved overall survival in
patients with advanced non-small-cell lung cancer (NSCLC). We aimed to investigate …

Nivolumab plus ipilimumab as first-line treatment for advanced non-small-cell lung cancer (CheckMate 012): results of an open-label, phase 1, multicohort study

MD Hellmann, NA Rizvi, JW Goldman… - The lancet …, 2017 - thelancet.com
Background Nivolumab has shown improved survival in the treatment of advanced non-
small-cell lung cancer (NSCLC) previously treated with chemotherapy. We assessed the …

[HTML][HTML] First-line nivolumab plus ipilimumab with two cycles of chemotherapy versus chemotherapy alone (four cycles) in advanced non-small-cell lung cancer …

M Reck, TE Ciuleanu, M Cobo, M Schenker… - ESMO open, 2021 - Elsevier
Background To further characterize survival benefit with first-line nivolumab plus ipilimumab
with two cycles of chemotherapy versus chemotherapy alone, we report updated data from …

[HTML][HTML] Nivolumab plus ipilimumab in advanced non–small-cell lung cancer

MD Hellmann, L Paz-Ares… - … England Journal of …, 2019 - Mass Medical Soc
Background In an early-phase study involving patients with advanced non–small-cell lung
cancer (NSCLC), the response rate was better with nivolumab plus ipilimumab than with …

Nivolumab (NIVO) plus ipilimumab (IPI) versus chemotherapy (chemo) as first-line (1L) treatment for advanced non-small cell lung cancer (NSCLC): 4-year update …

LG Paz-Ares, TE Ciuleanu, JS Lee, L Urban… - 2021 - ascopubs.org
9016 Background: 1L NIVO+ IPI was shown to provide durable long-term overall survival
(OS) benefit vs chemo regardless of tumor programmed death ligand 1 (PD-L1) expression …

First-line nivolumab plus ipilimumab in advanced non–small-cell lung cancer (CheckMate 568): outcomes by programmed death ligand 1 and tumor mutational …

N Ready, MD Hellmann, MM Awad… - Journal of Clinical …, 2019 - ascopubs.org
PURPOSE CheckMate 568 is an open-label phase II trial that evaluated the efficacy and
safety of nivolumab plus low-dose ipilimumab as first-line treatment of advanced/metastatic …

Effectiveness and safety of nivolumab in advanced non-small cell lung cancer: the real-life data

E Dudnik, M Moskovitz, S Daher, S Shamai… - Lung cancer, 2018 - Elsevier
Objectives Nivolumab has recently received regulatory approval as a 2nd-line treatment of
non-small cell lung cancer (NSCLC). The data regarding its effectiveness and safety in real …

Nivolumab monotherapy for first-line treatment of advanced non–small-cell lung cancer

S Gettinger, NA Rizvi, LQ Chow, H Borghaei… - Journal of Clinical …, 2016 - ascopubs.org
Purpose Nivolumab, a programmed death-1 (PD-1) immune checkpoint inhibitor antibody,
has demonstrated improved survival over docetaxel in previously treated advanced non …

Overall survival and long-term safety of nivolumab (anti–programmed death 1 antibody, BMS-936558, ONO-4538) in patients with previously treated advanced non …

SN Gettinger, L Horn, L Gandhi, DR Spigel… - Journal of clinical …, 2015 - ascopubs.org
Purpose Programmed death 1 is an immune checkpoint that suppresses antitumor immunity.
Nivolumab, a fully human immunoglobulin G4 programmed death 1 immune checkpoint …

Four-year survival with nivolumab in patients with previously treated advanced non-small-cell lung cancer: a pooled analysis

SJ Antonia, H Borghaei, SS Ramalingam… - The Lancet …, 2019 - thelancet.com
Background Phase 3 clinical data has shown higher proportions of patients with objective
response, longer response duration, and longer overall survival with nivolumab versus …