Piperacillin extends the spectrum of activity of ampicillin to include most strains of
Pseudomonas aeruginosa, Enterobacteriaceae (non-β-lactamase-producing), many …

Piperacillin/tazobactam is a β-lactam/β-lactamase inhibitor combination with a broad
spectrum of antibacterial activity encompassing most Gram-positive and Gram-negative …

The in vitro activity of piperacillin alone or titrated with a constant concentration of 4 μg/ml
tazobactam was evaluated against 3962 baseline pathogens isolated from 1899 patients …

Synopsis Combining tazobactam, a β-lactamase inhibitor, with the ureidopenicillin,
piperacillin, successfully restores the activity of piperacillin against β-lactamase-producing …

The safety of piperacillin/tazobactam was investigated in Phase I and Phase III clinical
studies. In 22 Phase I pharmacokinetic studies, 242 healthy subjects and 232 patients were …

Piperacillin/tazobactam is the most recently approved combination of a β-lactam agent with
an inhibitor of bacterial β-lactamases. It has a broader spectrum than do preceding inhibitor …

Piperacillin–tazobactam is a β-lactam/β-lactamase inhibitor combination with a broad
spectrum of antibacterial activity that includes Gram-positive and-negative aerobic and …

Discussion Piperacillin/tazobactam is a b-lactam/b-lactamase inhibitor combination with a
broad spectrum of antibacterial activity against most gram-positive and gram-negative …

Objective: To discuss the antimicrobial activity, pharmacokinetics, clinical efficacy, and
adverse effect profile of piperacillin/tazobactam, a new beta-lactam/beta-lactamase inhibitor …

Intra-abdominal infections are a serious problem for surgeons. Treatment consists of a
combination of operation, antimicrobial treatment, and supportive measures. beta-Lactam …