Alpha-fetoprotein and its relevance to human disease

HT Wepsic, A Kirkpatrick - Gastroenterology, 1979 - Elsevier
Alpha-1-fetoprotein(AFP) is a serum protein found in high concentrations in fetal blood,
maternal blood, and in the blood of adult animals with hepatomas, and rarely, with other …

Alpha-fetoprotein in primary liver cancer and other diseases.

M Kew - Gut, 1974 - ncbi.nlm.nih.gov
Alpha-fetoprotein (AFP) is an alpha1 globulin normally present in high concentration in fetal
serum but in only very small amounts thereafter. Although many of its physico-chemical …

Serum alphafetoprotein in hepatocellular carcinoma

DS Chen, JL Sung - Cancer, 1977 - Wiley Online Library
The serum alphafetoprotein level (AFP) was studied in 125 histologically verified cases of
hepatocellular carcinoma, 66 other malignancies, 74 cases of cirrhosis of the liver, 60 of …

Alpha-fetoprotein: occurrence in certain malignant diseases and review of clinical applications

JB Smith - The Medical clinics of North America, 1970 - pubmed.ncbi.nlm.nih.gov
PIP: Several large studies have established the usefulness of alpha fetoprotein (AFP)
detection as a diagnostic test in patients suspected of having primary hepatoma. in the …

α-Fetoprotein in human hepatoma: improved detection in serum, and quantitative studies using a new sensitive technique

E Alpert, R Hershberg, PH Schur, KJ Isselbacher - Gastroenterology, 1971 - Elsevier
α-Fetoprotein (AFP) was measured in the sera of 62 patients from the United States and 58
foreign patients with hepatoma. AFP was detected in 50.5% of these patients by double …

Alpha1-Fetoprotein

S Sell, HT Wepsic - Western Journal of Medicine, 1975 - ncbi.nlm.nih.gov
ALPHA1-FETOPROTEIN (AFP) is a serum protein found in low concentrations in normal
adults (< 10 nanogram (ng) per ml); concentrations well above this are found in fetal serum …

Alpha-fetoprotein in the routine clinical laboratory: Evaluation of a simple radioimmunoassay and review of current concepts in its clinical application

W Brummund, DA Aryan, MT Mennuti… - Clinica Chimica Acta, 1980 - Elsevier
We have assessed the clinical utility of a radioimmunoassay for alpha-fetoprotein (AFP). The
method, which relies on ammonium sulfate precipitation for the separation of “bound” and …

[引用][C] Serum alpha-fetoprotein in nonneoplastic liver diseases

JR Bloomer - Digestive diseases and sciences, 1980 - Springer
The association between serum alpha-fetoprotein (AFP) and transplantable hepatocellular
carcinoma in mice was reported by the Russian investigator Abelev in 1963. Subsequent …

α-Fetoprotein: reevaluation in hepatology

K Taketa - Hepatology, 1990 - journals.lww.com
KAZUHISA TAKETA in Hepatology a-Fetoprotein (AFP) is a fetal serum protein (1, 2), and its
reappearance in mice with hepatoma was demonstrated by Abelev et al.(3) in 1963 and in …

Radioimmunoassay of α-fetoprotein in human serum: Clinical value in patients with liver diseases

JAP Chayvialle, C Touillon, C Crozier… - The American Journal of …, 1974 - Springer
A radioimmunoassay for human α 1-fetoprotein (AFP) has been developed. Serum AFP
level was measured in 136 healthy adults, the mean value±sd being 3.8±1.3 ng/ml of serum …