Surface engineered dendrimers as antiangiogenic agent and carrier for anticancer drug: dual attack on cancer

K Jain, NK Jain - Journal of nanoscience and nanotechnology, 2014 - ingentaconnect.com
The present research work describes the formulation of arginine conjugated 3.0 G Poly
(propylene) imine (PPI) dendrimers, mimicking the surface structure of an endogenous …

[HTML][HTML] Scalable production and in vitro efficacy of inhaled erlotinib nanoemulsion for enhanced efficacy in non-small cell lung cancer (NSCLC)

G Chauhan, X Wang, C Yousry, V Gupta - Pharmaceutics, 2023 - mdpi.com
Non-small cell lung cancer (NSCLC) is a global concern as one of the leading causes of
cancer deaths. The treatment options for NSCLC are limited to systemic chemotherapy …

Dendrimers as nanoscale vectors: Unlocking the bars of cancer therapy

AD Dey, A Bigham, Y Esmaeili, M Ashrafizadeh… - Seminars in Cancer …, 2022 - Elsevier
Chemotherapy is the first choice in the treatment of cancer and is always preferred to other
approaches such as radiation and surgery, but it has never met the need of patients for a …

Ligand anchored dendrimers based nanoconstructs for effective targeting to cancer cells

U Gupta, SKD Dwivedi, HK Bid, R Konwar… - International journal of …, 2010 - Elsevier
Dendrimers are considered versatile carriers especially for the treatment of diseases like
cancer, AIDS, malaria etc. Cancer is a worldwide threat particularly in developing countries …

Dendrimer-based nanoparticulate delivery system for cancer therapy

R Shukla, A Singh, V Pardhi, K Kashyap… - … nanoparticles as a …, 2019 - Elsevier
Past eras reported cancer as the most challenging ailment affecting human lives worldwide
with a common presence in developed countries that prevails to this date. The progress in …

A PEGylated dendritic nanoparticulate carrier of fluorouracil

D Bhadra, S Bhadra, S Jain, NK Jain - International journal of …, 2003 - Elsevier
The present study was aimed at developing and exploring the use of uncoated and
PEGylated newer PAMAM dendrimers for delivery of anti-cancer drug 5-fluorouracil. For this …

Synthesis and characterization of poly (propylene imine)-dendrimer-grafted gold nanoparticles as nanocarriers of doxorubicin

M Golshan, M Salami-Kalajahi, M Mirshekarpour… - Colloids and Surfaces B …, 2017 - Elsevier
The aim of current work is synthesis 4th-generation-poly (propylene imine)(PPI)-dendrimer
modified gold nanoparticles (Au-G4A) as nanocarriers for doxorubicin (DOX) and studying in …

Erlotinib entrapped in cholesterol-depleting cyclodextrin nanoparticles shows improved antitumoral efficacy in 3D spheroid tumors of the lung and the liver

G Varan, S Akkın, N Demirtürk, JM Benito… - Journal of drug …, 2021 - Taylor & Francis
Erlotinib (ERL), a tyrosine kinase inhibitor approved for therapeutic use in non-small cell
lung cancer is further researched for eventual liver cancer treatment. However, conventional …

Exploiting gelatin nanocarriers in the pulmonary delivery of methotrexate for lung cancer therapy

H Abdelrady, RM Hathout, R Osman, I Saleem… - European journal of …, 2019 - Elsevier
Gelatin has many merits that encourage its use in the pulmonary delivery of anticancer
drugs. It is a biodegradable denatured protein which possesses several functional groups …

Microparticles containing erlotinib-loaded solid lipid nanoparticles for treatment of non-small cell lung cancer

Z Bakhtiary, J Barar, A Aghanejad, AA Saei… - Drug development …, 2017 - Taylor & Francis
Non-small cell lung cancer (NSCLC) patients with sensitizing mutations in the exons 18–21
of the epithelial growth factor receptor (EGFR) gene show increased kinase activity of EGFR …