Cancer targeting potential of some ligand-anchored poly (propylene imine) dendrimers: a comparison

P Kesharwani, RK Tekade, V Gajbhiye, K Jain… - … , Biology and Medicine, 2011 - Elsevier
The present investigation was aimed at developing and comparing the cancer-targeting
potential of ligand-anchored dendrimers. Folate-, dextran-, and galactose-anchored poly …

Reversal of EGFR inhibitors' resistance by co-delivering EGFR and integrin αvβ3 inhibitors with nanoparticles in non-small cell lung cancer

F He, Y Wang, W Cai, M Li, L Dong - Bioscience reports, 2019 - portlandpress.com
Purpose: Tumor cells, with drug resistance, are associated with failed treatment and poor
prognosis. Our aim was to explore potential strategy to overcome the epidermal growth …

Conclusion and future considerations of dendrimers

S Singh, G Singh, S Sehrawat, P Rawat… - Dendrimer-based …, 2021 - Elsevier
Dendrimers are new hyperbranched globular and three-dimensional nanocarrier.
Dendrimer nanocarriers are emergent as most attractive nanocarrier for gene and drug …

Enzyme-responsive peptide dendrimer-gemcitabine conjugate as a controlled-release drug delivery vehicle with enhanced antitumor efficacy

C Zhang, D Pan, J Li, J Hu, A Bains, N Guys, H Zhu… - Acta biomaterialia, 2017 - Elsevier
Stimuli-responsive peptide dendrimer-drug conjugates have presented significant potential
for cancer therapy. To develop an effective nanoscale chemotherapeutic prodrug, we …

Surface modified dendrimers: synthesis and characterization for cancer targeted drug delivery

A Sharma, SP Gautam, AK Gupta - Bioorganic & medicinal chemistry, 2011 - Elsevier
Dendrimers represents a highly branched three-dimensional structure that provides a high
degree of surface functionality and versatility. PAMAM dendrimers are used as well-defined …

Generation dependent safety and efficacy of folic acid conjugated dendrimer based anticancer drug formulations

P Kesharwani, RK Tekade, NK Jain - Pharmaceutical research, 2015 - Springer
Purpose Folate conjugated poly (propyleneimine)(PPI) dendrimer (FPPI) mediated
anticancer therapy is being extensively discovered throughout the world. The present …

Dendrimer nanoarchitectures for cancer diagnosis and anticancer drug delivery

AK Sharma, A Gothwal, P Kesharwani, H Alsaab… - Drug Discovery …, 2017 - Elsevier
Highlights•Dendrimers are efficient nanocarriers having biomedical and diagnostic
application potentials.•Dendrimers can be efficiently encapsulated with drugs by host–guest …

Development and characterization of surface engineered PPI dendrimers for targeted drug delivery

A Kaur, K Jain, NK Mehra, NK Jain - Artificial cells, nanomedicine …, 2017 - Taylor & Francis
In this study, we reported folate-conjugated polypropylene imine dendrimers (FA–PPI) as
efficient carrier for model anticancer drug, methotrexate (MTX), for pH-sensitive drug …

Dextran conjugated dendritic nanoconstructs as potential vectors for anti-cancer agent

A Agarwal, U Gupta, A Asthana, NK Jain - Biomaterials, 2009 - Elsevier
The purpose of the present investigation was to evaluate the potential of surface engineered
polypropylene imine (PPI) dendrimers as nanoscale drug delivery units for site-specific …

Exploring dendrimer-based drug delivery systems and their potential applications in cancer immunotherapy

S Mukherjee, S Mukherjee, MAS Abourehab… - European Polymer …, 2022 - Elsevier
Cancer immunotherapy has been researched as a major modality of treatment which
involves activating the immune system of the patient to fight against tumor cells. Dendrimers …