Development and characterization of surface engineered PPI dendrimers for targeted drug delivery
In this study, we reported folate-conjugated polypropylene imine dendrimers (FA–PPI) as
efficient carrier for model anticancer drug, methotrexate (MTX), for pH-sensitive drug …
efficient carrier for model anticancer drug, methotrexate (MTX), for pH-sensitive drug …
[HTML][HTML] Cellular internalization and transport of biodegradable polyester dendrimers on a model of the pulmonary epithelium and their formulation in pressurized …
The purpose of this study was to evaluate the effect of generation and surface PEGylation of
degradable polyester-based dendrimers nanocarriers on their interactions with an in vitro …
degradable polyester-based dendrimers nanocarriers on their interactions with an in vitro …
Design of biocompatible dendrimers for cancer diagnosis and therapy: current status and future perspectives
Y Cheng, L Zhao, Y Li, T Xu - Chemical Society Reviews, 2011 - pubs.rsc.org
In the past decade, nanomedicine with its promise of improved therapy and diagnostics has
revolutionized conventional health care and medical technology. Dendrimers and dendrimer …
revolutionized conventional health care and medical technology. Dendrimers and dendrimer …
[PDF][PDF] Dendrimer-based nanoparticles in cancer chemotherapy and gene therapy
This review discusses recent studies on dendrimer-based nanoparticles in cancer
chemotherapy and gene therapy. In order to achieve the high efficacy and low side effects of …
chemotherapy and gene therapy. In order to achieve the high efficacy and low side effects of …
Dendrimers for pulmonary delivery: current perspectives and future challenges
Dendrimers and dendrimer-based delivery systems are potential biomedicines in the rapidly
growing field of nanomedicine. At present, dendrimers are drawing attention in the scientific …
growing field of nanomedicine. At present, dendrimers are drawing attention in the scientific …
Dendrimer-mediated delivery of anticancer drugs for colon cancer treatment
The third most common cancer worldwide is colon cancer (CC). Every year, there more
cases are reported, yet there are not enough effective treatments. This emphasizes the need …
cases are reported, yet there are not enough effective treatments. This emphasizes the need …
PAMAM dendrimers as efficient drug and gene delivery nanosystems for cancer therapy
Drug delivery systems for cancer chemotherapy are employed to improve the effectiveness
and decrease the side-effects of highly toxic drugs. Most chemotherapy agents have …
and decrease the side-effects of highly toxic drugs. Most chemotherapy agents have …
Stealth dendrimers for drug delivery: correlation between PEGylation, cytocompatibility, and drug payload
H Yang, ST Lopina, LP DiPersio… - Journal of Materials …, 2008 - Springer
It is advantageous to utilize low generation polyamidoamine (PAMAM) dendrimers for drug
delivery because low generations (generation 4.0 or below) have more biologically …
delivery because low generations (generation 4.0 or below) have more biologically …
Effect of the route of administration and PEGylation of poly (amidoamine) dendrimers on their systemic and lung cellular biodistribution
There are many opportunities in the development of oral inhalation (oi) formulations for the
delivery of small molecule therapeutics and biologics to and through the lungs. Nanocarriers …
delivery of small molecule therapeutics and biologics to and through the lungs. Nanocarriers …
[HTML][HTML] Gefitinib-loaded starch nanoparticles for battling lung cancer: Optimization by full factorial design and in vitro cytotoxicity evaluation
Lung cancer is the number one killer among all cancer types. For decades, clinicians have
been using conventional chemotherapeutics, but they can't rely on them alone anymore …
been using conventional chemotherapeutics, but they can't rely on them alone anymore …