Dendrimer nanoparticles for colorectal cancer applications

MR Carvalho, RL Reis, JM Oliveira - Journal of Materials Chemistry B, 2020 - pubs.rsc.org
Cancer nanotechnology is a prolific field of research, where nanotools are employed to
diagnose and treat cancer with unprecedented precision. Targeted drug delivery is …

Pegylated dendrimer and its effect in fluorouracil loading and release for enhancing antitumor activity

TU Ly, NQ Tran, TKD Hoang, KN Phan… - Journal of …, 2013 - ingentaconnect.com
Dendrimer, a new class of hyper-branched polymer with predetermined molecular weight, is
being received much attention in nano biomedical applications such as anticancer drug …

Covalently coupling doxorubicin to polymeric nanoparticles as potential inhaler therapy: in vitro studies

G Ak - Pharmaceutical Development and Technology, 2021 - Taylor & Francis
Lung cancer is the most commonly diagnosed type of cancer worldwide, non-small cell lung
cancer accounts for most lung cancers. Doxorubicin is a widely used chemotherapy agent in …

Effective targeting of gemcitabine to pancreatic cancer through PEG-cored Flt-1 antibody-conjugated dendrimers

K Öztürk, G Esendağlı, MU Gürbüz, M Tülü… - International journal of …, 2017 - Elsevier
Tumor-targeted delivery of anticancer drugs using dendrimers has been recognized as a
promising strategy to increase efficiency and reduce adverse effects of chemotherapy …

Synthesis and evaluation of polyethylene glycol-and folic acid-conjugated polyamidoamine G4 dendrimer as nanocarrier

A Narmani, J Mohammadnejad, K Yavari - Journal of Drug Delivery Science …, 2019 - Elsevier
Synthesis of folic-acid mediated targeting nanocarrier is one of the most important and
effective approaches in drug delivery. In this study, firstly, the surface of polyamidoamine G4 …

Octa-arginine modified poly (amidoamine) dendrimers for improved delivery and cytotoxic effect of paclitaxel in cancer

SVK Rompicharla, P Kumari, B Ghosh… - Artificial Cells …, 2018 - Taylor & Francis
Cell penetrating peptides (CPP) have the ability to penetrate the cell membrane and have
been associated with various cargos for their facile intracellular translocation. The current …

[HTML][HTML] Amphiphilic dendritic nanomicelle-mediated delivery of gemcitabine for enhancing the specificity and effectiveness

W Zhao, S Yang, C Li, F Li, H Pang, G Xu… - International Journal …, 2022 - ncbi.nlm.nih.gov
Purpose Gemcitabine is the first line and the gold standard drug for pancreatic cancer.
However, the anticancer efficacy is severely limited by its instability and poor cellular uptake …

Enhanced Codelivery of Gefitinib and Azacitidine for Treatment of Metastatic-Resistant Lung Cancer Using Biodegradable Lipid Nanoparticles

EM Elzayat, AY Sherif, FA Nasr, MW Attwa, DH Alshora… - Materials, 2023 - mdpi.com
Lung cancer is a formidable challenge in clinical practice owing to its metastatic nature and
resistance to conventional treatments. The codelivery of anticancer agents offers a potential …

Tweaking dendrimers and dendritic nanoparticles for controlled nano-bio interactions: Potential nanocarriers for improved cancer targeting

J Bugno, H Hsu, S Hong - Journal of drug targeting, 2015 - Taylor & Francis
Nanoparticles have shown great promise in the treatment of cancer, with a demonstrated
potential in targeted drug delivery. Among a myriad of nanocarriers that have been recently …

Tumor targeting using polyamidoamine dendrimer–cisplatin nanoparticles functionalized with diglycolamic acid and herceptin

A Kesavan, P Ilaiyaraja, WS Beaula, VV Kumari… - European Journal of …, 2015 - Elsevier
Polymer mediated drug delivery system represents a novel promising platform for tumor-
targeting with reduced systemic side effects and improved chemotherapeutical efficacy. In …