[HTML][HTML] Dendritic macromolecules as nano-scale drug carriers: Phase solubility, in vitro drug release, hemolysis and cytotoxicity study
Potential of nanoscale triazine based dendritic macromolecules G1, G2 and G3 as solubility
enhancers of drug was investigated. Effect of pH, concentration and generation of …
enhancers of drug was investigated. Effect of pH, concentration and generation of …
Biodistribution characteristics of amino acid dendrimers and their PEGylated derivatives after intravenous administration
T Okuda, S Kawakami, T Maeie, T Niidome… - Journal of controlled …, 2006 - Elsevier
In this study, we synthesized dendritic poly (l-lysine) s (DPKs), dendritic poly (l-ornithine) s
(DPOs), which are constructed as novel amino acid dendrimers, and PEGylated KG6 (the …
(DPOs), which are constructed as novel amino acid dendrimers, and PEGylated KG6 (the …
Synthesis, dynamics and applications (cytotoxicity and biocompatibility) of dendrimers: A mini-review
Dendrimers are an excellent candidate that exhibits higher proficiency in biomedical
applications such as drug delivery, inhibition and/or targeting gene delivery. The use of …
applications such as drug delivery, inhibition and/or targeting gene delivery. The use of …
Preparation and evaluation of peptide-dendrimer-paclitaxel conjugates for treatment of heterogeneous stage 1 nonsmall cell lung cancer in 293T and L132 cell lines
W Zhang, Y Wang, X Kan, X Wang, D Geng - Tropical Journal of …, 2017 - ajol.info
Purpose: To develop peptide-dendrimer-paclitaxel conjugates for the treatment of
heterogeneous stage 1 non small cell lung cancer (NSCLC) in 293T and L132cell line …
heterogeneous stage 1 non small cell lung cancer (NSCLC) in 293T and L132cell line …
Dendrimers based cancer nanotheranostics: An overview
Cancer is a known deadliest disease that requires a judicious diagnostic, targeting, and
treatment strategy for an early prognosis and selective therapy. The major pitfalls of the …
treatment strategy for an early prognosis and selective therapy. The major pitfalls of the …
Recent advances in oncological submissions of dendrimer
N Soni, M Tekade, P Kesharwani… - Current …, 2017 - ingentaconnect.com
Background: Disseminated metastatic cancer requires insistent management owing to its
reduced responsiveness for chemotherapeutic agents, toxicity to normal cells consequently …
reduced responsiveness for chemotherapeutic agents, toxicity to normal cells consequently …
Recent progress in dendrimer-based nanomedicine development
Y Kim, EJ Park, DH Na - Archives of pharmacal research, 2018 - Springer
Dendrimers offer well-defined nanoarchitectures with spherical shape, high degree of
molecular uniformity, and multiple surface functionalities. Such unique structural properties …
molecular uniformity, and multiple surface functionalities. Such unique structural properties …
Co-delivery of metformin and silibinin in dual-drug loaded nanoparticles synergistically improves chemotherapy in human non-small cell lung cancer A549 cells
F Mogheri, E Jokar, R Afshin, AA Akbari… - Journal of Drug Delivery …, 2021 - Elsevier
Combination of nanoparticle (NP)-based therapeutic methods with chemotherapy has
suggested a potent strategy to increase the intracellular concentrations of drugs and …
suggested a potent strategy to increase the intracellular concentrations of drugs and …
In vitro and in vivo uptake studies of PAMAM G4. 5 dendrimers in breast cancer
N Oddone, N Lecot, M Fernández… - Journal of …, 2016 - Springer
Background Breast cancer is the second leading cause of cancer death worldwide.
Nanotechnology approaches can overcome the side effects of chemotherapy as well as …
Nanotechnology approaches can overcome the side effects of chemotherapy as well as …
Surface modified and rituximab functionalized PAMAM G4 nanoparticle for targeted imatinib delivery to leukemia cells: In vitro studies
P Fotouhi, S Sohrabi, N Nosrati, AZ Vaziri… - Process …, 2021 - Elsevier
Cancer therapy is one of the most important issues in human beings' life since it is the
determining cause of death all over the world. In this research, polyethylene glycol (P: PEG) …
determining cause of death all over the world. In this research, polyethylene glycol (P: PEG) …