[HTML][HTML] Adipose tissue development and lipid metabolism in the human fetus: The 2020 perspective focusing on maternal diabetes and obesity

G Desoye, E Herrera - Progress in Lipid Research, 2021 - Elsevier
During development, the human fetus accrues the highest proportion of fat of all mammals.
Precursors of fat lobules can be found at week 14 of pregnancy. Thereafter, they expand …

Lipid metabolism in the fetus and the newborn

E Herrera, E Amusquivar - Diabetes/metabolism research and …, 2000 - Wiley Online Library
During late gestation, although maternal adipose tissue lipolytic activity becomes enhanced,
lipolytic products cross the placenta with difficulty. Under fasting conditions, free fatty acids …

[HTML][HTML] Adipose tissue and fetal programming

ME Symonds, M Pope, D Sharkey, H Budge - Diabetologia, 2012 - Springer
Adipose tissue function changes with development. In the newborn, brown adipose tissue
(BAT) is essential for ensuring effective adaptation to the extrauterine environment, and its …

Early-life programming of adipose tissue

E Moreno-Mendez, S Quintero-Fabian… - Nutrition Research …, 2020 - cambridge.org
Worldwide obesity is increasing at an alarming rate in children and adolescents, with the
consequent emergence of co-morbidities. Moreover, the maternal environment during …

[HTML][HTML] Maternal and fetal lipid metabolism under normal and gestational diabetic conditions

E Herrera, G Desoye - Hormone molecular biology and clinical …, 2016 - degruyter.com
Maternal lipids are strong determinants of fetal fat mass. Here we review the overall lipid
metabolism in normal and gestational diabetes mellitus (GDM) pregnancies. During early …

Altered maternal and placental lipid metabolism and fetal fat development in obesity: Current knowledge and advances in non-invasive assessment

F Delhaes, SA Giza, T Koreman, G Eastabrook… - Placenta, 2018 - Elsevier
Abnormal maternal lipid profiles, a hallmark of increased maternal adiposity, are associated
with pregnancy complications such as preeclampsia and gestational diabetes, and offspring …

[HTML][HTML] Developmental programming of offspring adipose tissue biology and obesity risk

A Rodgers, AN Sferruzzi-Perri - International Journal of Obesity, 2021 - nature.com
Obesity is reaching epidemic proportions and imposes major negative health crises and an
economic burden in both high and low income countries. The multifaceted nature of obesity …

Maternal lipids and fetal overgrowth: making fat from fat

LA Barbour, TL Hernandez - Clinical therapeutics, 2018 - Elsevier
There is increasing recognition that maternal glucose concentrations lower than those
previously used for diagnosis of gestational diabetes mellitus (GDM) and targeted for …

Maternal factors that determine neonatal size and body fat

PM Catalano, JP Kirwan - Current diabetes reports, 2001 - Springer
These data are a review of previously published data. Initially, body composition was
estimated in 186 neonates. Fatfree mass (FFM), which constituted 86% of birth weight …

Lipid metabolism in pregnancy and its consequences in the fetus and newborn

E Herrera - Endocrine, 2002 - Springer
During early pregnancy there is an increase in body fat accumulation, associated with both
hyperphagia and increased lipogenesis. During late pregnancy there is an accelerated …