OBJECTIVE: Changes in metabolic homeostasis in pregnant diabetic women are potential
determinants of increased adiposity of the fetus. The aim of this study was to characterize …

As obesity reaches epidemic levels in the United States there is an urgent need to
understand the developmental pathways leading to this condition. Obesity increases the risk …

Recent studies have established that the neonate born to a pregnancy with maternal
diabetes or obesity ('diabesity') is characterized by increased fat accumulation. The neonatal …

During the first half of gestation in the rat, maternal net body weight increases rapidly,
whereas in the second half of gestation, the mass of maternal structures declines, coincident …

Excess bodyweight is the sixth most important risk factor contributing to the overall burden of
disease worldwide. In excess of a billion adults and 10% of all children are now classified as …

Background: The increasing incidence of childhood obesity is a significant public health
challenge, the consequences of which extend across the life course. Summary: Diet and …

Context: The impact of specific maternal fuels and metabolic measures during early and late
gestation on neonatal body composition is not well defined. Objective: To determine how …

Recent observational studies suggest that mean birth weight and body fat growth in the first
year of life have increased continuously over the last decades. Both elevated birth weight …

Maternal fatty acid and lipid metabolism undergoes changes during pregnancy to facilitate
fetal growth and development. Different types of fatty acids have different roles in …

Based on the concept of Developmental Origin of Health and Disease, both human and
animal studies have demonstrated a close link between nutrient supply perturbations in the …