[PDF][PDF] Characterization of the new htau-KI mouse model for Alzheimer's disease with a focus on the role of immune cells during progressing cerebral amyloidosis
S Barendrecht - 2021 - opendata.uni-halle.de
1.1 Background of Alzheimer's disease Alzheimer's disease (AD) is a neurodegenerative
disorder, first presented by the German physician Alois Alzheimer in 1906. In the 4 …
disorder, first presented by the German physician Alois Alzheimer in 1906. In the 4 …
A TauP301L mouse model of dementia; development of pathology, synaptic transmission, microglial response and cognition throughout life
Z Joel, P Izquierdo, W Liu, C Hall, M Roberts, K Yap… - BioRxiv, 2018 - biorxiv.org
Abstract Background Late stage Alzheimer's disease and other dementias are associated
with neurofibrillary tangles and neurodegeneration. Here we describe a mouse (TauD35) …
with neurofibrillary tangles and neurodegeneration. Here we describe a mouse (TauD35) …
EXPERIMENTAL MODELS OF ALZHEIMER'S DISEASE
AM ERCAN - Alzheimer's Disease From Molecular Mechanisms to … - books.google.com
Alzheimer's disease (AD) is becoming increasingly common as the global population ages.
The World Health Organization (WHO) estimates that 1 billion people were over the age of …
The World Health Organization (WHO) estimates that 1 billion people were over the age of …
Peripheral adaptive immunity of the triple transgenic mouse model of Alzheimer's disease
I St-Amour, CR Bosoi, I Paré… - Journal of …, 2019 - Springer
Background Immunologic abnormalities have been described in peripheral blood and
central nervous system of patients suffering from Alzheimer's disease (AD), yet their role in …
central nervous system of patients suffering from Alzheimer's disease (AD), yet their role in …
Modeling Alzheimer's disease: considerations for a better translational and replicable mouse model
Alzheimer's disease (AD) mouse models have proven to be an invaluable tool for deepening
our understanding of disease mechanisms and for developing therapeutics. However, one …
our understanding of disease mechanisms and for developing therapeutics. However, one …
[HTML][HTML] Characterization of Transgenic Mouse Models of Alzheimer's Disease and Related Dementia
LC Camargo - docserv.uni-duesseldorf.de
Beschreibungen: Alzheimer's disease (AD) is a complex neurodegenerative disorder with
multiple features. With the help of animal models, the AD physiopathology is starting to be …
multiple features. With the help of animal models, the AD physiopathology is starting to be …
Animal models of Alzheimer's disease
S Amram, D Frenkel - Neuroprotection in Alzheimer's Disease, 2017 - Elsevier
Alzheimer's disease (AD) is the most common type of dementia. The pathological
characterizations of AD are the depositions of a peptide called amyloid beta and of hyper …
characterizations of AD are the depositions of a peptide called amyloid beta and of hyper …
[HTML][HTML] Murine models of Alzheimer's disease and their use in developing immunotherapies
T Wisniewski, EM Sigurdsson - … et Biophysica Acta (BBA)-Molecular Basis …, 2010 - Elsevier
Alzheimer's disease (AD) is one of the categories of neurodegenerative diseases
characterized by a conformational change of a normal protein into a pathological conformer …
characterized by a conformational change of a normal protein into a pathological conformer …
[HTML][HTML] Animal models of Alzheimer's disease
G Casadesus, G Arendash, F Laferla… - International journal of …, 2010 - ncbi.nlm.nih.gov
The necessity for a deeper understanding of neurological diseases such as Alzheimer's
disease (AD) that increase in frequency as a function of age has become of paramount …
disease (AD) that increase in frequency as a function of age has become of paramount …
Mouse models of Alzheimer's disease
M Yokoyama, H Kobayashi, L Tatsumi… - Frontiers in Molecular …, 2022 - frontiersin.org
Alzheimer's disease (AD) is a neurodegenerative disorder characterized by memory loss
and personality changes, eventually leading to dementia. The pathological hallmarks of AD …
and personality changes, eventually leading to dementia. The pathological hallmarks of AD …