Antiviral Effect of Ginsenosides Rk1 against Influenza a Virus Infection by Targeting the Hemagglutinin 1-Mediated Virus Attachment

X Yang, H Sun, Z Zhang, W Ou, F Xu, L Luo… - International Journal of …, 2023 - mdpi.com
Influenza A virus (IAV) infections have been a serious hazard to public health everywhere.
With the growing concern of drug-resistant IAV strains, there is an urgent need for novel anti …

Inhibition of influenza A virus infection by ginsenosides

W Dong, A Farooqui, AJ Leon, DJ Kelvin - PLoS One, 2017 - journals.plos.org
Influenza viruses cause mild to severe respiratory infections in humans. Due to efficient
means of transmission, the viruses infect human population on a large scale. Apart from …

A small molecule compound targeting hemagglutinin inhibits influenza A virus and exhibits broad-spectrum antiviral activity

Y Li, G Liang, Z Chen, K Zhang, J Liang… - Acta Pharmacologica …, 2024 - nature.com
Influenza A virus (IAV) is a widespread pathogen that poses a significant threat to human
health, causing pandemics with high mortality and pathogenicity. Given the emergence of …

Antiviral effect of isoquercitrin against influenza A viral infection via modulating hemagglutinin and neuraminidase

WK Cho, MM Lee, JY Ma - International Journal of Molecular Sciences, 2022 - mdpi.com
Isoquercitrin (IQC) is a component abundantly present in many plants and is known to have
an anti-viral effect against various viruses. In this study, we demonstrate that IQC exhibits …

Quercetin as an antiviral agent inhibits influenza A virus (IAV) entry

W Wu, R Li, X Li, J He, S Jiang, S Liu, J Yang - Viruses, 2015 - mdpi.com
Influenza A viruses (IAVs) cause seasonal pandemics and epidemics with high morbidity
and mortality, which calls for effective anti-IAV agents. The glycoprotein hemagglutinin of …

[HTML][HTML] Rosmarinic acid interferes with influenza virus A entry and replication by decreasing GSK3β and phosphorylated AKT expression levels

JR Jheng, CF Hsieh, YH Chang, JY Ho… - Journal of Microbiology …, 2022 - Elsevier
Background The purpose of this study was to examine the in vivo activity of rosmarinic acid
(RA)–a phytochemical with antioxidant, anti-inflammatory, and antiviral properties–against …

Identification of novel virus inhibitors by influenza A virus specific reporter cell based screening

J Zhang, T Liu, X Tong, G Li, J Yan, X Ye - Antiviral research, 2012 - Elsevier
As influenza viruses have developed resistance towards current drugs, it is urgent to find
potential novel antiviral inhibitors. Here we generated an influenza virus reporter cell line in …

An oleanolic acid derivative inhibits hemagglutinin-mediated entry of influenza A virus

M Ye, Y Liao, L Wu, W Qi, N Choudhry, Y Liu, W Chen… - Viruses, 2020 - mdpi.com
Influenza A viruses (IAV) have been a major public health threat worldwide, and options for
antiviral therapy become increasingly limited with the emergence of drug-resisting virus …

The Cranberry Extract Oximacro® Exerts in vitro Virucidal Activity Against Influenza Virus by Interfering With Hemagglutinin

A Luganini, ME Terlizzi, G Catucci, G Gilardi… - Frontiers in …, 2018 - frontiersin.org
The defense against influenza virus (IV) infections still poses a series of challenges. The
current antiviral arsenal against influenza viruses is in fact limited; therefore, the …

Ginsenoside Rb1 enhanced immunity and altered the gut microflora in mice immunized by H1N1 influenza vaccine

C Wan, R Lu, C Zhu, H Wu, G Shen, Y Yang, X Wu… - PeerJ, 2023 - peerj.com
Background Influenza is an acute infectious respiratory disease caused by the influenza
virus that seriously damages human health, and the essential way to prevent influenza is the …