Sublingual Immunotherapy Efficacy of Dermatophagoides farinae Vaccine in a Murine Asthma Model

H Yu, X Li, H Guo, Z Liu, P Ran, K Ji… - International archives of …, 2010 - karger.com
Background: Allergen-specific sublingual immunotherapy is a potential treatment for allergic
diseases. Its effective dose and underlying mechanism are still to be explored. Here, we …

The efficacy of sublingual immunotherapy with Dermatophagoides farinae vaccine in a murine atopic dermatitis model

L Liu, D Guo, Q Liang, S Ding, B Wu… - Clinical & …, 2015 - Wiley Online Library
Background Sublingual immunotherapy (SLIT) is a potential treatment for house dust mite‐
induced atopic dermatitis (AD). However, the mechanisms of action are not clear. Objective …

Sublingual immunotherapy for experimental allergic conjunctivitis in a murine model induced by Dermatophagoides farinae allergen

L Liu, D Guo, Q Liang, S Ding, J Chen, B Wu… - International Archives of …, 2013 - karger.com
Background: Sublingual immunotherapy (SLIT) is a clinically effective treatment in allergic
conjunctivitis (AC); however, the mechanism of the underlying pharmacodynamics remains …

Oral administration of allergen extracts from Dermatophagoides farinae desensitizes specific allergen-induced inflammation and airway hyperresponsiveness in rats

Q Xie, X Wu, H Wu, Y Deng, S Zhang, J Zhu… - International …, 2008 - Elsevier
Clinically sublingual immunotherapy (SLIT) by using allergen extracts effectively alleviates
the symptoms of allergic rhinitis and asthma. Supposed that oral administration of high-dose …

Effects of sublingual immunotherapy in a murine asthma model sensitized by intranasal administration of house dust mite extracts

K Shima, T Koya, K Tsukioka, T Sakagami… - Allergology …, 2017 - jstage.jst.go.jp
Background: Sublingual immunotherapy (SLIT) has received attention as a method for
allergen immu-notherapy. However, the mechanism of SLIT has not yet been fully …

Subcutaneous immunotherapy with purified Der p1 and 2 suppresses type 2 immunity in a murine asthma model

L Hesse, N van Ieperen, C Habraken, AH Petersen… - Allergy, 2018 - Wiley Online Library
Background Allergen‐specific immunotherapy can induce long‐term suppression of allergic
symptoms, reduce medication use, and prevent exacerbations of allergic rhinitis and …

Local nasal immunotherapy: efficacy of Dermatophagoides farinae-chitosan vaccine in murine asthma

Z Liu, H Guo, Y Wu, H Yu, H Yang, J Li - International archives of allergy …, 2009 - karger.com
Background: Local nasal immunotherapy has been reported to be effective for airway
allergic diseases. A biodegradable material, chitosan (CS), has been reported to be safe …

Sublingual immunotherapy with Dermatophagoides monomeric allergoid down‐regulates allergen‐specific immunoglobulin E and increases both interferon‐γ‐ and …

L Cosmi, V Santarlasci, R Angeli… - Clinical & …, 2006 - Wiley Online Library
Background The clinical efficacy and safety of sublingual immunotherapy (SLIT) for
aeroallergens has been demonstrated in several trials, whereas the immunological changes …

House dust mite-specific sublingual immunotherapy prevents the development of allergic inflammation in a mouse model of experimental asthma

S Hagner, C Rask, J Brimnes, PS Andersen… - International archives of …, 2016 - karger.com
Background: Evidence regarding sublingual immunotherapy (SLIT) efficacy and its good
safety profile has been demonstrated with pollen and house dust mite (HDM) allergens in …

Production of salivary immunoglobulin A and suppression of Dermatophagoides pteronyssinus-induced airway inflammation by local nasal immunotherapy

YH Liu, JJ Tsai - International archives of allergy and immunology, 2005 - karger.com
Background: Local nasal immunotherapy (LNIT) is an effective immunotherapeutic modality,
especially when targeting a single immunodominant peptide from an allergen. However, the …