Double-stranded DNA and RNA, and DNA/RNA hybrids form naturally in cells between two
nucleic acid strands containing complementary sequences. However, these double …

Helicases are the proteins that bind to double-or single-stranded DNA and/or RNA chains to
unwind higher order structures, usually consuming energy from the hydrolysis of ATP …

DNA helicases are molecular motors that catalyse the unwinding of energetically unstable
structures into single strands and have therefore an essential role in nearly all metabolism …

DNA helicases have emerged as a prominent class of nucleic acid-metabolizing enzymes
that play important roles in genome maintenance and cellular homeostasis. DNA helicases …

Since the discovery of the DNA double helix, there has been a fascination in understanding
the molecular mechanisms and cellular processes that account for:(i) the transmission of …

DNA helicases have emerged as a prominent class of nucleic acid-metabolizing enzymes
that play important roles in genome maintenance and cellular homeostasis. DNA helicases …

To date, numerous genes have been identified to encode helicases, which are enzymes that
unwind DNA/DNA, DNA/RNA and RNA/RNA duplexes to regulate DNA replication …

Helicases are ubiquitous enzymes that disrupt complementary strands of duplex nucleic
acid in a reaction dependent on nucleoside-5′-triphosphate hydrolysis. Helicases are …

First discovered in the 1970s, DNA helicases were initially described as enzymes that use
chemical energy to separate (ie, to unwind) the complementary strands of DNA. Because …

Most processes involving an organism's genetic material, including replication, repair and
recombination, require access to single-stranded DNA as a template or reaction …