Eslicarbazepine acetate

M Bialer, C Elger - The Treatment of Epilepsy, 2015 - Wiley Online Library
Eslicarbazepine acetate (ESL) is a voltage‐gated sodium and calcium channel blocker that
was identified as a promising candidate for clinical development in epilepsy through a drug …

Clinical utility of eslicarbazepine: current evidence

G Zaccara, F Giovannelli, M Cincotta… - Drug design …, 2015 - Taylor & Francis
Eslicarbazepine acetate (ESL) is a new antiepileptic drug whose mechanism of action is
blockade of the voltage-gated sodium channel (VGSC). However, in respect to …

Eslicarbazepine acetate: its effectiveness as adjunctive therapy in clinical trials and open studies

SD Shorvon, E Trinka, BJ Steinhoff, M Holtkamp… - Journal of …, 2017 - Springer
Eslicarbazepine acetate (ESL) is a once-daily antiepileptic drug that is approved as
adjunctive therapy in adults with focal-onset seizures. Following oral administration, ESL is …

Clinical response and tolerability of eslicarbazepine in treatment of partial onset seizures: impact of a novel metabolic pathway

E Serrano, CL Harden - Journal of Receptor, Ligand and Channel …, 2011 - Taylor & Francis
Epilepsy is a common chronic neurological condition affecting 50 million people worldwide.
Because at least 30% of patients with partial seizures do not achieve seizure control with the …

Eslicarbazepine acetate: an update on efficacy and safety in epilepsy

A Verrotti, G Loiacono, A Rossi, G Zaccara - Epilepsy research, 2014 - Elsevier
Epilepsy is a common neurological disorder. Despite a broad range of commonly used
antiepileptic drugs, approximately 30% of patients with epilepsy have drug resistance or …

Eslicarbazepine acetate: A novel agent for the adjunctive treatment of epilepsy.

RT Owen - Drugs of Today (Barcelona, Spain: 1998), 2010 - europepmc.org
Eslicarbazepine acetate, a novel antiepileptic agent, has recently been marketed as an
adjunctive therapy in adults with partial onset seizures with or without secondary …

Eslicarbazepine acetate for the treatment of partial epilepsy

J Zelano, E Ben-Menachem - Expert Opinion on Pharmacotherapy, 2016 - Taylor & Francis
Introduction: Eslicarbazepine acetate (ESL) is a third generation AED structurally related to
carbamazepine and oxcarbazepine, but without several of the drawbacks associated with …

Update on the role of eslicarbazepine acetate in the treatment of partial-onset epilepsy

R Tambucci, C Basti, M Maresca… - Neuropsychiatric …, 2016 - Taylor & Francis
Eslicarbazepine acetate (ESL) is a once daily new third generation antiepileptic drug that
shares the basic chemical structure of carbamazepine and oxcarbazepine–a dibenzazepine …

[HTML][HTML] Eslicarbazepine: Pharmacokinetics and Drug Interactions

KT Kim, YW Cho - Epilia: Epilepsy and Community, 2022 - jepilia.org
Eslicarbazepine acetate is an advanced antiseizure medication that is an improvement upon
carbamazepine and oxcarbazepine. This novel antiseizure medication regulates voltage …

Eslicarbazepine acetate for the treatment of focal epilepsy: an update on its proposed mechanisms of action

P Soares‐da‐Silva, N Pires… - Pharmacology …, 2015 - Wiley Online Library
Eslicarbazepine acetate (ESL) is a once daily antiepileptic drug (AED) approved by the
European Medicines Agency (EMA), the Food and Drug Administration (FDA) and Health …