Using 18F-NOS PET Imaging to Measure Pulmonary Inflammation in Electronic and Combustible Cigarette Users: A Pilot Study

RR Wetherill, RK Doot, AJ Young, H Lee, EK Schubert… - medRxiv, 2022 - medrxiv.org
Electronic cigarette (EC) use has increased dramatically, particularly among adolescents
and young adults, which, like cigarette use, can cause inflammation of the lungs and …

Molecular imaging of pulmonary inflammation in users of electronic and combustible cigarettes: a pilot study

RR Wetherill, RK Doot, AJ Young, H Lee… - Journal of Nuclear …, 2023 - Soc Nuclear Med
Electronic cigarette (EC) use has increased dramatically, particularly among adolescents
and young adults, and, like cigarette use, can cause pulmonary inflammation and increase …

[PDF][PDF] Reply: Molecular Imaging of Pulmonary Inflammation: Claiming That Vaping Is More Harmful Than Smoking Is Unsupported

RR Wetherill, J Dubroff - Journal of Nuclear Medicine, 2023 - Soc Nuclear Med
In our innovative pilot study, we found increased radiotracer binding of 18F-6-(1/2)(2-
fluoropropyl)-4-methylpyridin-2-amine (18F-NOS) in the lungs of electronic cigarette users …

Short-term effect of e-cigarette use on spirometry and FENO on young adults

SL Burress, TJC Diamond, JB Waugh - 2019 - rc.rcjournal.com
Background: There is limited research on the effects of vaping with electronic nicotine
delivery systems (ENDS). Inflammation markers and morphological lung changes have …

MRI shows lung perfusion changes after vaping and smoking

S Nyilas, G Bauman, I Korten, O Pusterla, F Singer… - Radiology, 2022 - pubs.rsna.org
Background Evidence regarding short-term effects of electronic nicotine delivery systems
(ENDS) and tobacco smoke on lung ventilation and perfusion is limited. Purpose To …

[HTML][HTML] Systemic biomarkers in electronic cigarette users: implications for noninvasive assessment of vaping-associated pulmonary injuries

KP Singh, G Lawyer, T Muthumalage… - ERJ Open …, 2019 - Eur Respiratory Soc
Background Electronic cigarettes (e-cigs) were introduced as electronic nicotine delivery
systems, and have become very popular in the USA and globally. There is a paucity of data …

[HTML][HTML] Exhaled nitric oxide levels in COPD patients who use electronic cigarettes

A Higham, A Beech, D Singh - Nitric Oxide, 2024 - Elsevier
Emerging data from clinical studies have shown pro-inflammatory effects associated with e-
cigarette use. Fractional exhaled nitric oxide (FeNO) is a biomarker of pulmonary type 2 (T2) …

E-Cigarette Aerosol Deposition and Disposition of [11C]Nicotine Using Positron Emission Tomography: A Comparison of Nicotine Uptake in Lungs and Brain Using …

A Wall, S Roslin, B Borg, S McDermott, T Walele… - Pharmaceuticals, 2022 - mdpi.com
Smoking is a cause of serious disease in smokers. Electronic cigarettes, delivering
aerosolized nicotine, offer adult smokers a potentially less harmful alternative to combustible …

An RCT of acute health effects in COPD-patients after passive vape exposure from e-cigarettes

K Rosenkilde Laursen, JH Bønløkke… - European clinical …, 2021 - Taylor & Francis
Background: E-cigarette use has been shown to have short-term acute effects among active
users but less is known of the acute passive effects, particularly among individuals with …

Quantification of regional murine ozone-induced lung inflammation using [18F]F-FDG microPET/CT imaging

GK Aulakh, M Kaur, V Brown, S Ekanayake, B Khan… - Scientific Reports, 2020 - nature.com
Ozone (O3) is a highly potent and reactive air pollutant. It has been linked to acute and
chronic respiratory diseases in humans by inducing inflammation. Our studies have found …