Virus spike and membrane-lytic mimicking nanoparticles for high cell binding and superior endosomal escape
Virus-inspired mimics for gene therapy have attracted increasing attention because viral
vectors show robust efficacy owing to the highly infectious nature and efficient endosomal …
vectors show robust efficacy owing to the highly infectious nature and efficient endosomal …
Virus-inspired nanosystems for drug delivery
With over millions of years of evolution, viruses can infect cells efficiently by utilizing their
unique structures. Similarly, the drug delivery process is designed to imitate the viral …
unique structures. Similarly, the drug delivery process is designed to imitate the viral …
Cell membrane-derived biomimetic nanodecoys for viruses
Viruses cause numerous acute, chronic and life-threatening infectious diseases, and remain
a major public health problem worldwide. The wide-spreading and highly pathogenic …
a major public health problem worldwide. The wide-spreading and highly pathogenic …
Biomedical nanoparticle design: What we can learn from viruses
SM Figueroa, D Fleischmann, A Goepferich - Journal of Controlled Release, 2021 - Elsevier
Viruses are nanomaterials with a number of properties that surpass those of many synthetic
nanoparticles (NPs) for biomedical applications. They possess a rigorously ordered …
nanoparticles (NPs) for biomedical applications. They possess a rigorously ordered …
Carrier-free nanodrug-based virus-surface-mimicking nanosystems for efficient drug/gene co-delivery
Nature-inspired nanoparticles, from pathogens to mammalian cells, have attracted
increasing attention, for their specific functions and unparalled features that are often …
increasing attention, for their specific functions and unparalled features that are often …
Virus-derived materials: bury the hatchet with old foes
Although enormous attempts are being made to develop synthetic materials for biomedical
applications, more and more attention has been paid to bioderived materials due to their …
applications, more and more attention has been paid to bioderived materials due to their …
Viral mimicry as a design template for nucleic acid nanocarriers
IF de la Fuente, SS Sawant, MQ Tolentino… - Frontiers in …, 2021 - frontiersin.org
Therapeutic nucleic acids hold immense potential in combating undruggable, gene-based
diseases owing to their high programmability and relative ease of synthesis. While the …
diseases owing to their high programmability and relative ease of synthesis. While the …
[引用][C] Chemically tailored multivalent virus platforms: From drug delivery to catalysis
AK Udit, CPR Hackenberger, MK O'Reilly - ChemBioChem, 2010 - Wiley Online Library
Polyvalent scaffolds offer versatile platforms from which to build potent multifunctional
materials. The numerous examples and applications include dendrimers, dendrons, and …
materials. The numerous examples and applications include dendrimers, dendrons, and …
Virus-inspired design principles of nanoparticle-based bioagents
The highly effectiveness and robustness of receptor-mediated viral invasion of living cells
shed lights on the biomimetic design of nanoparticle (NP)-based therapeutics. Through …
shed lights on the biomimetic design of nanoparticle (NP)-based therapeutics. Through …
[PDF][PDF] Nanoparticles mimicking viral surface topography for enhanced cellular delivery
The delivery of various drug molecules into cells is crucial in modern medicine.[1, 2] Most
naked biomolecules and some free drugs are poorly delivered to cells owing to poor …
naked biomolecules and some free drugs are poorly delivered to cells owing to poor …