Virus spike and membrane-lytic mimicking nanoparticles for high cell binding and superior endosomal escape

S Liu, J Yang, H Jia, H Zhou, J Chen… - ACS applied materials & …, 2018 - ACS Publications
Virus-inspired mimics for gene therapy have attracted increasing attention because viral
vectors show robust efficacy owing to the highly infectious nature and efficient endosomal …

Virus-inspired nanosystems for drug delivery

Z Liao, L Tu, X Li, XJ Liang, S Huo - Nanoscale, 2021 - pubs.rsc.org
With over millions of years of evolution, viruses can infect cells efficiently by utilizing their
unique structures. Similarly, the drug delivery process is designed to imitate the viral …

Cell membrane-derived biomimetic nanodecoys for viruses

X Liu, D Li, G Liu - Science China. Life Sciences, 2020 - ncbi.nlm.nih.gov
Viruses cause numerous acute, chronic and life-threatening infectious diseases, and remain
a major public health problem worldwide. The wide-spreading and highly pathogenic …

Biomedical nanoparticle design: What we can learn from viruses

SM Figueroa, D Fleischmann, A Goepferich - Journal of Controlled Release, 2021 - Elsevier
Viruses are nanomaterials with a number of properties that surpass those of many synthetic
nanoparticles (NPs) for biomedical applications. They possess a rigorously ordered …

Carrier-free nanodrug-based virus-surface-mimicking nanosystems for efficient drug/gene co-delivery

X Sun, M Li, Y Yang, H Jia, W Liu - Biomaterials science, 2018 - pubs.rsc.org
Nature-inspired nanoparticles, from pathogens to mammalian cells, have attracted
increasing attention, for their specific functions and unparalled features that are often …

[HTML][HTML] Viral mimicry as a design template for nucleic acid nanocarriers

IF de la Fuente, SS Sawant, MQ Tolentino… - Frontiers in …, 2021 - frontiersin.org
Therapeutic nucleic acids hold immense potential in combating undruggable, gene-based
diseases owing to their high programmability and relative ease of synthesis. While the …

Virus-derived materials: bury the hatchet with old foes

J Wu, H Wu, S Nakagawa, J Gao - Biomaterials science, 2020 - pubs.rsc.org
Although enormous attempts are being made to develop synthetic materials for biomedical
applications, more and more attention has been paid to bioderived materials due to their …

[PDF][PDF] Nanoparticles mimicking viral surface topography for enhanced cellular delivery

Y Niu, M Yu, SB Hartono, J Yang, H Xu, H Zhang… - Adv. Mater, 2013 - academia.edu
The delivery of various drug molecules into cells is crucial in modern medicine.[1, 2] Most
naked biomolecules and some free drugs are poorly delivered to cells owing to poor …

Virus-inspired design principles of nanoparticle-based bioagents

H Yuan, C Huang, S Zhang - PloS one, 2010 - journals.plos.org
The highly effectiveness and robustness of receptor-mediated viral invasion of living cells
shed lights on the biomimetic design of nanoparticle (NP)-based therapeutics. Through …

Living virus‐based nanohybrids for biomedical applications

L Jin, Z Mao - Wiley Interdisciplinary Reviews: Nanomedicine …, 2024 - Wiley Online Library
Living viruses characterized by distinctive biological functions including specific targeting,
gene invasion, immune modulation, and so forth have been receiving intensive attention …