Canonical non-homologous end joining (C-NHEJ) factors can assemble into a long-range
(LR) complex with DNA ends relatively far apart that contains DNAPKcs, XLF, XRCC4, LIG4 …

DNA double-strand break (DSB) repair by non-homologous end joining (NHEJ) in human
cells is initiated by Ku heterodimer binding to a DSB, followed by recruitment of core NHEJ …

Ku heterodimer is essential for the repair of DNA double-strand breaks (DSBs) by non-
homologous end-joining (NHEJ). Ku recruits XLF, also known as Cernunnos, to DSBs. Here …

Non‐homologous end‐joining (NHEJ) is the dominant means of repairing chromosomal
DNA double strand breaks (DSBs), and is essential in human cells. Fifteen or more proteins …

Nonhomologous end joining (NHEJ) plays a major role in double-strand break DNA repair,
which involves a series of steps mediated by multiprotein complexes. A ring-shaped …

The nonhomologous DNA end-joining (NHEJ) pathway is a key mechanism for repairing
dsDNA breaks that occur often in eukaryotic cells. In the simplest model, these breaks are …

Non‐homologous end joining (NHEJ) is critical for the maintenance of genetic integrity and
DNA double‐strand break (DSB) repair. NHEJ is regulated by a series of interactions …

In mammalian cells, non‐homologous end joining (NHEJ) is the major double strand break
(DSB) repair mechanism during the G1 phase of the cell cycle. It also contributes to DSB …

Classical nonhomologous end joining (C-NHEJ) is a major mammalian DNA double-strand
break (DSB) repair pathway that is required for assembly of antigen receptor variable region …

Non-homologous end joining (NHEJ) is one of two critical mechanisms utilized in humans to
repair DNA double-strand breaks (DSBs). Unrepaired or incorrect repair of DSBs can lead to …