Should antidepressants be avoided in pregnancy?

FMC Besag, MJ Vasey - Drug Safety, 2023 - Springer
Abstract Many (> 40%) women discontinue antidepressants during pregnancy because of
concerns about effects on the foetus, based on information from inadequately-controlled …

Prenatal antidepressant exposure: clinical and preclinical findings

CH Bourke, ZN Stowe, MJ Owens - Pharmacological reviews, 2014 - ASPET
Pharmacological treatment of any maternal illness during pregnancy warrants consideration
of the consequences of the illness and/or medication for both the mother and unborn child …

Birth outcomes following prenatal exposure to antidepressants

KH Pearson, RM Nonacs, AC Viguera… - Journal of Clinical …, 2007 - psychiatrist.com
Background: Antidepressant use during pregnancy and the peripartum period is common
despite the absence of clear evidence-based guidelines to direct clinical use of these …

The risks associated with prenatal antidepressant exposure: time for a precision medicine approach

LH Pedersen - Expert opinion on drug safety, 2017 - Taylor & Francis
Introduction: The prevalence of depression in pregnancy is over 10% and a significant
proportion of pregnant women use antidepressant medication. The safety of antidepressants …

A systematic review of maternal antidepressant use in pregnancy and short-and long-term offspring's outcomes

SL Prady, I Hanlon, LK Fraser… - Archives of women's …, 2018 - Springer
The relative safety of antidepressants during pregnancy has received substantial attention,
but most syntheses fail to account for mental illness effects. We aimed to evaluate the …

Disparities in antidepressant use in pregnancy

A Yamamoto, MC McCormick, HH Burris - Journal of Perinatology, 2015 - nature.com
Objective: The American College of Obstetricians and Gynecologists and the American
Psychiatric Association both recommend pharmacotherapy for perinatal depression when …

Increasing use of antidepressants in pregnancy

WO Cooper, ME Willy, SJ Pont, WA Ray - American journal of obstetrics and …, 2007 - Elsevier
OBJECTIVE: The purpose of this study was to quantify the rate of exposures to
antidepressants during pregnancy in a large cohort of women. STUDY DESIGN: This was a …

Associations of maternal antidepressant use during the first trimester of pregnancy with preterm birth, small for gestational age, autism spectrum disorder, and attention …

AC Sujan, ME Rickert, AS Öberg, PD Quinn… - Jama, 2017 - jamanetwork.com
Importance Prenatal antidepressant exposure has been associated with adverse outcomes.
Previous studies, however, may not have adequately accounted for confounding. Objective …

Maternal use of specific antidepressant medications during early pregnancy and the risk of selected birth defects

KN Anderson, JN Lind, RM Simeone, WV Bobo… - JAMA …, 2020 - jamanetwork.com
Importance Antidepressants are commonly used during pregnancy, but limited information is
available about individual antidepressants and specific birth defect risks. Objective To …

Neonatal and childhood outcomes in offspring of pregnant women using antidepressant medications: a critical review of current meta‐analyses

F Uguz - The Journal of Clinical Pharmacology, 2021 - Wiley Online Library
This article reviewed the results of 21 recent meta‐analyses examining the relationship
between maternal use of antidepressants during pregnancy and negative outcomes in …