Aim: To evaluate the relationship between CYP genetic polymorphisms and CYP metabolite
levels with carotid artery stenosis in acute ischemic stroke (IS) patients. Methods: Eleven …

Background The mechanisms of neurologic deterioration (ND) are not fully understood. The
aim of the present study was to evaluate the relationship between CYP genetic variants and …

Aim: To better understand the relationship between the interactions among rs17110453,
rs751141, and rs9333025 variants and plasma levels of cytochrome P450 (CYP) …

Aim: Cytochrome P450s (CYP450) enzymes regulate inflammation and atherosclerosis and
can affect carotid plaque stability in patients with ischemic stroke (IS). This study aimed to …

Stroke is a major cause of morbidity and mortality worldwide. Genetic and environmental
factors are involved in the pathogenesis of stroke. Hypertension, diabetes mellitus, and …

Aim: Ischemic stroke (IS) is a multifactorial disease caused by environmental risk factors and
genetic susceptibility. However, few studies have assessed whether gene–gene interactions …

The human cytochrome P450 (CYP) superfamily includes at least 57 genes that encode
enzymes with diverse metabolic and biosynthetic functions. This study was conducted in …

Backgrounds Stroke is a sudden disorder of cerebral blood circulation. Many studies have
illustrated that dyslipidemia, hypertension, diabetes, smoking and excessive drinking are the …

The aim of this study was to investigate the association between CYP1A1 gene
polymorphism and ischaemic stroke (IS) risk, and the impact of gene–gene interaction on IS …

Background The association between aldosterone synthase (CYP11B2) C-344T gene
polymorphism and ischemic stroke remains controversial and ambiguous. To better explain …