Exploring joint patterns of brain structure and function in inflammatory bowel diseases using multimodal data fusion

AK Thomann, MM Schmitgen, D Kmuche… - …, 2021 - Wiley Online Library
Background A growing number of neuroimaging studies suggest distinct neural changes in
inflammatory bowel diseases (IBDs). Whether such changes may show similar spatial …

Multimodal brain MRI of deep gray matter changes associated with inflammatory bowel disease

BG Goodyear, F Heidari, RJM Ingram… - Inflammatory Bowel …, 2023 - academic.oup.com
Background Behavioral symptoms, including mood disorders, substantially impact the
quality of life of patients with inflammatory bowel disease (IBD), even when clinical …

Functional brain rewiring and altered cortical stability in ulcerative colitis

H Wang, JS Labus, F Griffin, A Gupta, RR Bhatt… - Molecular …, 2022 - nature.com
Despite recent advances, there is still a major need to better understand the interactions
between brain function and chronic gut inflammation and its clinical implications. Alterations …

Aberrant brain structural large‐scale connectome in Crohn's disease

AK Thomann, W Reindl, T Wüstenberg… - …, 2019 - Wiley Online Library
Background Disturbed brain‐gut interactions and a bidirectional relationship between
inflammation and psychiatric symptoms such as anxiety and depression are being …

Differential brain structural and functional patterns in Crohn's disease patients are associated with different disease stages

A Agostini, F Benuzzi, D Ballotta… - Inflammatory Bowel …, 2023 - academic.oup.com
Background Crohn's disease (CD) is an inflammatory, chronic disorder that alternates
between a quiescent phase and inflammatory flare-ups. Research has begun to elucidate …

Brain resting-state network alterations associated with Crohn's disease

J Kornelsen, A Wilson, JS Labus, K Witges… - Frontiers in …, 2020 - frontiersin.org
Inflammatory bowel disease (IBD) is a chronic disease that is associated with aspects of
brain anatomy and activity. In this preliminary MRI study, we investigated differences in brain …

New insights into the brain involvement in patients with Crohn's disease: a voxel‐based morphometry study

A Agostini, F Benuzzi, N Filippini… - …, 2013 - Wiley Online Library
Background Crohn's disease (CD) is a chronic intestinal disorder characterized by
overproduction of inflammatory cytokines and recurrent abdominal pain. Recently, brain …

The relationship between Central Nervous System morphometry changes and key symptoms in Crohn's disease

G Thapaliya, S Eldeghaidy, M Asghar, J McGing… - Brain Imaging and …, 2023 - Springer
Alterations in grey matter volume (GMV) and cortical thickness (CT) in Crohn's disease (CD)
patients has been previously documented. However, the findings are inconsistent, and not a …

Structural imaging changes and behavioral correlates in patients with Crohn's disease in remission

VA Nair, P Beniwal-Patel, I Mbah, BM Young… - Frontiers in Human …, 2016 - frontiersin.org
Background: Crohn's disease (CD) is a subtype of inflammatory bowel disease caused by
immune-mediated inflammation in the gastrointestinal tract. The extent of morphologic brain …

Brain functional changes in patients with Crohn's disease: A resting‐state fMRI study

L Li, J Ma, JG Xu, YL Zheng, Q Xie, L Rong… - Brain and …, 2021 - Wiley Online Library
Background Crohn's disease (CD) is a chronic recurrent intestinal inflammatory disease,
often accompanied by poor adaptation and excessive stress response. However, the …