Overview of iron metabolism in health and disease
Iron is an essential element for numerous fundamental biologic processes, but excess iron is
toxic. Abnormalities in systemic iron balance are common in patients with chronic kidney …
toxic. Abnormalities in systemic iron balance are common in patients with chronic kidney …
Disorders of iron metabolism and anemia in chronic kidney disease
B Panwar, OM Gutiérrez - Seminars in nephrology, 2016 - Elsevier
Dysregulated iron homeostasis plays a central role in the development of anemia of chronic
kidney disease (CKD) and is a major contributor toward resistance to treatment with …
kidney disease (CKD) and is a major contributor toward resistance to treatment with …
The iron cycle in chronic kidney disease (CKD): from genetics and experimental models to CKD patients
K Zumbrennen-Bullough, JL Babitt - Nephrology Dialysis …, 2014 - academic.oup.com
Iron is essential for most living organisms but iron excess can be toxic. Cellular and systemic
iron balance is therefore tightly controlled. Iron homeostasis is dysregulated in chronic …
iron balance is therefore tightly controlled. Iron homeostasis is dysregulated in chronic …
The multifaceted role of iron in renal health and disease
RPL van Swelm, JFM Wetzels… - Nature Reviews …, 2020 - nature.com
Iron is an essential element that is indispensable for life. The delicate physiological body
iron balance is maintained by both systemic and cellular regulatory mechanisms. The iron …
iron balance is maintained by both systemic and cellular regulatory mechanisms. The iron …
Positive iron balance in chronic kidney disease: how much is too much and how to tell?
JB Wish, GR Aronoff, BR Bacon, C Brugnara… - American journal of …, 2018 - karger.com
Background: Regulation of body iron occurs at cellular, tissue, and systemic levels. In
healthy individuals, iron absorption and losses are minimal, creating a virtually closed …
healthy individuals, iron absorption and losses are minimal, creating a virtually closed …
Iron metabolism in the pathogenesis of iron-induced kidney injury
AMF Martines, R Masereeuw, H Tjalsma… - Nature Reviews …, 2013 - nature.com
In the past 8 years, there has been renewed interest in the role of iron in both acute kidney
injury (AKI) and chronic kidney disease (CKD). In patients with kidney diseases, renal …
injury (AKI) and chronic kidney disease (CKD). In patients with kidney diseases, renal …
Iron homeostasis: new players, newer insights
ES Edison, A Bajel, M Chandy - European journal of …, 2008 - Wiley Online Library
Although iron is a relatively abundant element in the universe, it is estimated that more than
2 billion people worldwide suffer from iron deficiency anemia. Iron deficiency results in …
2 billion people worldwide suffer from iron deficiency anemia. Iron deficiency results in …
Iron deficiency in chronic kidney disease: updates on pathophysiology, diagnosis, and treatment
EK Batchelor, P Kapitsinou, PE Pergola… - Journal of the …, 2020 - journals.lww.com
Anemia is a complication that affects a majority of individuals with advanced CKD. Although
relative deficiency of erythropoietin production is the major driver of anemia in CKD, iron …
relative deficiency of erythropoietin production is the major driver of anemia in CKD, iron …
Understanding iron: promoting its safe use in patients with chronic kidney failure treated by hemodialysis
ND Vaziri - American journal of kidney diseases, 2013 - Elsevier
Although judicious use of intravenous iron preparations is an indispensable part of anemia
treatment in hemodialysis patients, their excessive and indiscriminate use can have …
treatment in hemodialysis patients, their excessive and indiscriminate use can have …
[HTML][HTML] Iron and anemia of chronic disease
G Weiss - Kidney international, 1999 - Elsevier
Iron and anemia of chronic disease. Anemia of chronic disease (ACD) is the most frequent
anemia found in hospitalized patients, often occurring in subjects suffering from chronic …
anemia found in hospitalized patients, often occurring in subjects suffering from chronic …