Time-restricted feeding prevents metabolic diseases through the regulation of galanin/GALR1 expression in the hypothalamus of mice

J Sun, Y She, P Fang, X Gu, Z Zhang - Eating and Weight Disorders …, 2022 - Springer
Purpose Time-restricted feeding (TRF) reverses obesity and insulin resistance, yet the
central mechanisms underlying its beneficial effects are not fully understood. Recent studies …

Diet‐induced obesity regulates the galanin‐mediated signaling cascade in the adipose tissue of mice

A Kim, T Park - Molecular nutrition & food research, 2010 - Wiley Online Library
Galanin is a neuropeptide that regulates the food intake, neurogenesis, memory, and gut
secretion. This study was conducted to evaluate the high‐fat diet (HFD)‐induced regulation …

Feeding behaviour in galanin knockout mice supports a role of galanin in fat intake and preference

AC Adams, JC Clapham, D Wynick… - Journal of …, 2008 - Wiley Online Library
It has been widely suggested that saturated fat consumption has fuelled the current obesity
epidemic. Macronutrient choices appear to be important not only as potential factors …

Galanin type 1 receptor knockout mice show altered responses to high-fat diet and glucose challenge

EP Zorrilla, M Brennan, V Sabino, X Lu, T Bartfai - Physiology & behavior, 2007 - Elsevier
Galanin, a brain and pancreatic peptide with three receptor subtypes (GALR1, GALR2, and
GALR3), is hypothesized to participate in energy homeostasis and glucoregulation …

Exaggerated feeding response to central galanin-like peptide administration in diet-induced obese rats

HM Tan, AL Gundlach, MJ Morris - Neuropeptides, 2005 - Elsevier
Galanin-like peptide (GALP) is a newly identified neuropeptide implicated in the regulation
of metabolism and reproduction. GALP gene expression is decreased in the hypothalamus …

Central nervous system regulation of food intake and energy expenditure: role of galanin-mediated feeding behavior

PH Fang, M Yu, YP Ma, J Li, YM Sui… - Neuroscience bulletin, 2011 - ncbi.nlm.nih.gov
Galanin is a neuropeptide widely expressed in the brain. It is implicated in energy
expenditure, feeding, and the regulation of body weight. Numerous studies have revealed …

Regulation of feeding behavior and energy metabolism by galanin-like peptide (GALP): A novel strategy to fight against obesity

F Takenoya, S Hirako, N Wada… - Current …, 2018 - ingentaconnect.com
Galanin-like peptide (GALP) is composed of 60 amino acid residues and its sequence is
highly homologous across species. GALP is produced in the hypothalamic arcuate nucleus …

Centrally administered galanin‐like peptide modifies food intake in the rat: a comparison with galanin

CB Lawrence, FMH Baudoin… - Journal of …, 2002 - Wiley Online Library
Galanin‐like peptide (GALP) is a recently identified neuropeptide that shares sequence
homology with the orexigenic neuropeptide, galanin. In contrast to galanin, GALP is reported …

Chronic increase of circulating galanin levels induces obesity and marked alterations in lipid metabolism similar to metabolic syndrome

NJ Poritsanos, TM Mizuno, ME Lautatzis… - International Journal of …, 2009 - nature.com
Objective: Galanin (GAL) has a role in the regulation of food intake by way of acting on the
central nervous system in rodents. High serum GAL levels have been observed in obese …

The effects of galanin‐like peptide on energy balance, body temperature and brain activity in the mouse and rat are independent of the GALR2/3 receptor

PS Man, CB Lawrence - Journal of neuroendocrinology, 2008 - Wiley Online Library
Galanin‐like peptide (GALP) is a neuropeptide that is thought to act on the galanin receptors
GALR1, GALR2 and GALR3. In rats, icv injection of GALP has dichotomous actions on …