Ischemia–reperfusion frequently occurs in ischemic cerebral vascular disease, during which
the inflammatory signaling plays essential roles. The aim of this study was to discover the …

The interleukins (ILs) are a pluripotent cytokine family that have been reported to regulate
ischemic stroke and cerebral ischemia/reperfusion (I/R) injury. IL‐22 is a member of the IL …

Abstract Background Interleukin-23 (IL-23) is required for T helper 17 (Th17) cell responses
and IL-17 production in ischemic stroke. We previously showed that the IL-23/IL-17 axis …

IL-35 has been identified as a novel anti-inflammatory cytokine that belongs to the IL-12
cytokine family and has been verified to play a protective role in autoimmune diseases. In …

Abstract Interleukin-23/interleukin-23 receptor (IL-23/IL-23R) has been implicated in many
inflammatory diseases. Previous research mainly focused on its ability to induce IL-17 …

Objective Inflammation and immune responses are crucial factors associated with the onset
and progression of stroke. Interleukin-11 (IL-11) is a hematopoietic IL-6 family cytokine that …

Stroke causes brain injury with neuroinflammation which exacerbates the neuronal damage.
Recent studies show that anti-inflammatory cytokine interleukin-19 (IL-19) plays a critical …

Ischemic stroke causes brain injury with activation of an inflammatory response that can
contribute to clinical impairment. As a novel cytokine of the interleukin-1 (IL-1) family, IL-33 …

Earlier this year the editorial office of CYTOKINE received an anonymous complaint that the
data in the paper “IL-37 reduces inflammatory response after cerebral ischemia and …

Background Interleukin-35 (IL-35), an anti-inflammatory and antioxidant cytokine, plays a
potent immunosuppressive role in various diseases. However, the effects of IL-35 on blood …