ROS-mediated genotoxicity induced by titanium dioxide nanoparticles in human epidermal cells

RK Shukla, V Sharma, AK Pandey, S Singh, S Sultana… - Toxicology in vitro, 2011 - Elsevier
Titanium dioxide nanoparticles (TiO2 NPs) are among the top five NPs used in consumer
products, paints and pharmaceutical preparations. Since, exposure to such nanoparticles is …

Oxidative stress-induced cytotoxic and genotoxic effects of nano-sized titanium dioxide particles in human HaCaT keratinocytes

A Jaeger, DG Weiss, L Jonas, R Kriehuber - Toxicology, 2012 - Elsevier
Since nano-sized particles (NPs) are increasingly used in various fields of innovative
biomedicine and industrial technologies, it is of importance to identify their potential human …

Long-term exposure of A549 cells to titanium dioxide nanoparticles induces DNA damage and sensitizes cells towards genotoxic agents

L Armand, A Tarantini, D Beal, M Biola-Clier… - …, 2016 - Taylor & Francis
Abstract Titanium dioxide nanoparticles (TiO2-NPs) are one of the most produced NPs in the
world. Their toxicity has been studied for a decade using acute exposure scenarios, ie high …

Titanium Dioxide Nanoparticles Induce DNA Damage and Genetic Instability In vivo in Mice

B Trouiller, R Reliene, A Westbrook, P Solaimani… - Cancer research, 2009 - AACR
Titanium dioxide (TiO2) nanoparticles are manufactured worldwide in large quantities for
use in a wide range of applications including pigment and cosmetic manufacturing. Although …

Genotoxic evaluation of titanium dioxide nanoparticles in vivo and in vitro

Z Chen, Y Wang, T Ba, Y Li, J Pu, T Chen, Y Song… - Toxicology letters, 2014 - Elsevier
With the extensive application of titanium dioxide (TiO 2) nanoparticles (NPs) in food
industry, there is a rising debate concerning the possible risk associated with exposure to …

TiO2 nanoparticles induce DNA double strand breaks and cell cycle arrest in human alveolar cells

K Kansara, P Patel, D Shah, RK Shukla… - Environmental and …, 2015 - Wiley Online Library
TiO2 nanoparticles (NPs) have the second highest global annual production (∼ 3000 tons)
among the metal‐containing NPs. These NPs are used as photocatalysts for bacterial …

Advances in genotoxicity of titanium dioxide nanoparticles in vivo and in vitro

J Shi, S Han, J Zhang, Y Liu, Z Chen, G Jia - NanoImpact, 2022 - Elsevier
Abstract Titanium dioxide nanoparticles (TiO 2 NPs) are currently one of the most widely
used nanomaterials. Due to an increasing scope of applications, the exposure of humans to …

Genotoxicity and gene expression analyses of liver and lung tissues of mice treated with titanium dioxide nanoparticles

Y Li, J Yan, W Ding, Y Chen, LM Pack, T Chen - Mutagenesis, 2017 - academic.oup.com
Abstract Titanium dioxide nanoparticles (TiO2 NPs) are used in paints, plastics, papers, inks,
foods, toothpaste, pharmaceuticals and cosmetics. However, TiO2 NPs cause inflammation …

Genotoxicity of TiO2 Nanoparticles in Four Different Human Cell Lines (A549, HEPG2, A172 and SH-SY5Y)

F Brandão, N Fernández-Bertólez, F Rosário… - Nanomaterials, 2020 - mdpi.com
Titanium dioxide nanoparticles (TiO2 NPs) have a wide variety of applications in many
consumer products, including as food additives, increasing the concern about the possible …

Titanium dioxide nanoparticle penetration into the skin and effects on HaCaT cells

M Crosera, A Prodi, M Mauro, M Pelin, C Florio… - International journal of …, 2015 - mdpi.com
Titanium dioxide nanoparticles (TiO2NPs) suspensions (concentration 1.0 g/L) in synthetic
sweat solution were applied on Franz cells for 24 h using intact and needle-abraded human …