Contribution of brain-derived neurotrophic factor to mechanical hyperalgesia induced by ventral root transection in rats
HS Chen, ZH Zhou, M Li, JX Wang, BJ Liu, Y Lu - Neuroreport, 2013 - journals.lww.com
It is generally believed that the development of neuropathic pain primarily results from
injuries to sensory afferent fibers. Recent studies found that injuries to the motor efferent …
injuries to sensory afferent fibers. Recent studies found that injuries to the motor efferent …
Contribution of capsaicin-sensitive primary afferents to mechanical hyperalgesia induced by ventral root transection in rats: the possible role of BDNF
W Li, JX Wang, ZH Zhou, Y Lu, XQ Li, BJ Liu… - Neurological …, 2016 - Taylor & Francis
Objective: A recent study showed that brain-derived neurotrophic factor (BDNF) may play a
role in the development of the neuropathic pain resulting from injury to motor efferent fibres …
role in the development of the neuropathic pain resulting from injury to motor efferent fibres …
Upregulation of brain-derived neurotrophic factor in the sensory pathway by selective motor nerve injury in adult rats
Selective motor nerve injury by lumbar 5 ventral root transection (L5 VRT) induces
neuropathic pain, but the underlying mechanisms remain unknown. Previously, increased …
neuropathic pain, but the underlying mechanisms remain unknown. Previously, increased …
Expression of brain-derived neurotrophic factor in rat dorsal root ganglia, spinal cord and gracile nuclei in experimental models of neuropathic pain
SO Ha, JK Kim, HS Hong, DS Kim, HJ Cho - Neuroscience, 2001 - Elsevier
Chronic constriction injury of the sciatic nerve and lumbar L5 and L6 spinal nerve ligation
provide animal models for pain syndromes accompanying peripheral nerve injury and …
provide animal models for pain syndromes accompanying peripheral nerve injury and …
The effect of site and type of nerve injury on the expression of brain-derived neurotrophic factor in the dorsal root ganglion and on neuropathic pain behavior
K Obata, H Yamanaka, K Kobayashi, Y Dai… - Neuroscience, 2006 - Elsevier
A number of rat neuropathy models have been developed to simulate human neuropathic
pain conditions, such as spontaneous pain, hyperalgesia, and allodynia. In the present …
pain conditions, such as spontaneous pain, hyperalgesia, and allodynia. In the present …
Brain-derived neurotrophic factor redistribution in the dorsal root ganglia correlates with neuropathic pain inhibition after resiniferatoxin treatment
GC Tender, YY Li, JG Cui - The Spine Journal, 2010 - Elsevier
BACKGROUND CONTEXT: Brain-derived neurotrophic factor (BDNF) and its cognate
receptor, the tyrosine kinase B (TrkB), are normally expressed in neurons and implicated in …
receptor, the tyrosine kinase B (TrkB), are normally expressed in neurons and implicated in …
Brain derived neurotrophic factor (BDNF) contributes to the pain hypersensitivity following surgical incision in the rats
CQ Li, JM Xu, D Liu, JY Zhang, RP Dai - Molecular pain, 2008 - journals.sagepub.com
Background: The pathogenic role of brain derived neurotrophic factor (BDNF) in the
incisional pain is poorly understood. The present study explores the role of the BDNF in the …
incisional pain is poorly understood. The present study explores the role of the BDNF in the …
Involvement of spinal cord BDNF in the generation and maintenance of chronic neuropathic pain in rats
L Constandil, R Aguilera, M Goich, A Hernández… - Brain research …, 2011 - Elsevier
Brain-derived neurotrophic factor (BDNF) is involved in neuronal survival and synaptic
plasticity of the central and peripheral nervous system. In chronic pain, plastic changes in …
plasticity of the central and peripheral nervous system. In chronic pain, plastic changes in …
Brain-derived neurotrophic factor modulates nociceptive sensory inputs and NMDA-evoked responses in the rat spinal cord
Central sensitization, the hyperexcitability of spinal processing that often accompanies
peripheral injury, is a major component of many persistent pain states. Here we report that …
peripheral injury, is a major component of many persistent pain states. Here we report that …
Brain-derived neurotrophic factor increases in the uninjured dorsal root ganglion neurons in selective spinal nerve ligation model
T Fukuoka, E Kondo, Y Dai, N Hashimoto… - Journal of …, 2001 - Soc Neuroscience
Nerve growth factor (NGF) and brain-derived neurotrophic factor (BDNF) are two major
members of the neurotrophin family. Using immunohistochemistry and in situ hybridization …
members of the neurotrophin family. Using immunohistochemistry and in situ hybridization …