Neisseria gonorrhoeae is a human-specific pathogen that causes gonorrhea, the second
most common sexually transmitted infection worldwide. Disease progression, drug …

As the COVID19 pandemic has taught us, research on the interactions between pathogenic
microorganisms and their hosts is vital not only for advancing our understanding of the …

Gonorrhea is the second most common sexually transmitted infection in the world and is
caused by Gram-negative diplococcus Neisseria gonorrhoeae. Since N. gonorrhoeae is a …

Mouse models of infection are important tools in the study of infectious disease or host the
development of products to prevent or treat infections. The estradiol-treated mouse model of …

The urogenital tract is a complex environment composed of many different types of epithelial
tissues and innate immune cells that sample the surrounding milieu. As a host-adapted …

Neisseria gonorrhoeae (gonococcus) causes the human sexually transmitted disease
gonorrhea. Studying gonococcal pathogenesis and developing new vaccines and therapies …

Murine models of Neisseria gonorrhoeae lower reproductive tract infection are valuable
systems for studying N. gonorrhoeae adaptation to the female host and immune responses …

Gonorrhea, caused by Neisseria gonorrhoeae, is a common sexually transmitted infection
and an urgent public health problem. Humans are the exclusive host, and the genital tract …

Liu et al.(2011) summarize our current understanding of how the gonococcus subverts the
immune system, and takes advantage of the immune privilege of the genital tract to foster an …

Background The emergence of fully antimicrobial resistant Neisseria gonorrhoeae has led
global public health agencies to identify a critical need for next generation anti-gonococcal …