Chronic inflammation is the main feature of many long-term inflammatory diseases such as
autoimmune diseases, metabolic disorders, and cancer. There is a growing number of …

Glycosylation is how proteins and lipids are modified with complex carbohydrates known as
glycans. The post-translational modification of proteins with glycans is not a template-driven …

Elevated glucose metabolism in immune cells represents a hallmark feature of many
inflammatory diseases, such as sepsis. However, the role of individual glucose metabolic …

N-linked glycosylation is a post-translational modification crucial for membrane protein
folding, stability and other cellular functions. Alteration of membrane protein N-glycans is …

Glycans are essential cellular components that facilitate a range of critical functions
important for tissue development and mucosal homeostasis. Furthermore, specific …

The immune system is highly controlled and fine-tuned by glycosylation, through the
addition of a diversity of carbohydrates structures (glycans) to virtually all immune cell …

The granulated neutrophils are abundant innate immune cells that utilize bioactive
glycoproteins packed in cytosolic granules to fight pathogenic infections, but the neutrophil …

The importance of protein glycosylation in the migration of immune cells throughout the body
has been extensively appreciated. However, our awareness of the impact of glycosylation …

The inflammatory response involves the activation of several cell types to fight insults
caused by a plethora of agents, and to maintain the tissue homoeostasis. On the one hand …

Chronic, low‑grade inflammation associated with obesity and diabetes result from the
infiltration of adipose and vascular tissue by immune cells and contributes to cardiovascular …